LuxSci
LuxSci: A compliance-focused email gateway for regulated healthcare communications, APIs, and campaigns. Ranked #40 of 178 in Email Hosting by our editors (5.3/10); pricing: Paid; best for healthcare and compliance-focused email gateways.
At a glance
- Editor score5.3 / 10
- PricingPaid
- Best forHealthcare and compliance-focused email gateways
- Free planNo
- Paid from$50/mo
- Founded1999 · Cambridge, Massachusetts, United States
- Facts checked21 Sep 2026

Where it wins
- Automatic encryption with secure portal, PGP, and S/MIME options
- HIPAA-compliant BAA, HITRUST certification, and audit trails
- Microsoft 365, Google Workspace, CRM, EHR, API, and webhook integrations
Where it doesn't
- No free plan and a $50 monthly entry price for Secure Gateway
- Secure Gateway pricing is centered on up to 40 users
- More focused on secure communications than ordinary mailbox hosting
Our verdict on LuxSci
LuxSci is secure healthcare communications software for healthcare providers, payers, suppliers, and other regulated organizations. Its product suite covers secure gateways for Microsoft 365 and Google Workspace, high-volume transactional email, secure email hosting, and HIPAA-compliant email marketing. The platform supports automated SecureLine encryption, secure portal escrow delivery, PGP and S/MIME, workflow automation, audit trails, and campaign reporting. It is best suited to organizations that need controlled email delivery and compliance-focused communication workflows rather than a basic mailbox service.
Published Secure Gateway plans run from $50 per month for up to 5 users to $280 per month for 40 users, with 10-, 20-, and 30-user tiers at $70, $140, and $210 per month. Each listed gateway tier includes automatic SecureLine encryption, a HIPAA-compliant BAA, Microsoft 365 and Google Workspace overlay, HITRUST certification, and ticket and phone support. Secure High Volume Email starts at $99 per month for up to 9,999 emails and reaches $299 per month for 30,000–49,999 emails. These plans add full email content encryption, REST API and SMTP access, and advanced API and webhooks.
LuxSci fits teams connecting secure email to existing healthcare and business systems. Integrations include Salesforce, HubSpot, Epic, and Cerner, while REST API and webhook access supports application-driven workflows. PHI-powered segmentation and personalization, automated campaigns, templates, and a drag-and-drop builder extend the platform beyond gateway routing. Its main limitation is focus: organizations seeking a simple, low-cost mailbox provider may find the compliance and communications scope broader than needed. Teams with regulated healthcare workflows, secure delivery requirements, or high-volume messaging should find the feature set more relevant.
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LuxSci pricing
All 12 LuxSci plans and prices →
LuxSci fact sheet
| Free plan | No |
|---|---|
| Paid from | $50/mo |
| Storage per mailbox | Not verified |
| Email aliases | Not verified |
| Attachment limit | Not verified |
| IMAP/POP support | Not verified |
| Mobile app access | Not verified |
| Calendar included | Not verified |
| Migration tools | Not verified |
| Deployment | Cloud, Self-hosted |
| Platforms | Web |
| Compliance & security | GDPR, HIPAA, SSO/SAML, 2FA |
| Support | Email, Phone, Tickets, Docs · 24/7 |
| Built for | Small business, Mid-market, Enterprise (editorial estimate) |
| Integrations | 8 integrations: Microsoft 365, Google Workspace, Salesforce, HubSpot, Epic, Cerner … |
| Pricing | Paid (source) |
| Website | luxsci.com |
| Facts checked | 21 Sep 2026 |
LuxSci integrations
LuxSci lists 8 integrations on its own site.
- Microsoft 365
- Google Workspace
- Salesforce
- HubSpot
- Epic
- Cerner
- REST API
- Webhooks
Alternatives to LuxSci
- Zoho MailA flexible business email suite with a free plan, low-cost entry tier, and migration support.9.4
- Microsoft Exchange OnlineA deep Exchange service for organizations centered on Outlook and administration.9.2
- Google WorkspaceA full Gmail-based collaboration suite for organizations that need more than email.9.1
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Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026
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