LuxSci review
A compliance-focused email gateway for regulated healthcare communications, APIs, and campaigns.
Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026
LuxSci is secure healthcare communications software for healthcare providers, payers, suppliers, and other regulated organizations. Its product suite covers secure gateways for Microsoft 365 and Google Workspace, high-volume transactional email, secure email hosting, and HIPAA-compliant email marketing. The platform supports automated SecureLine encryption, secure portal escrow delivery, PGP and S/MIME, workflow automation, audit trails, and campaign reporting. It is best suited to organizations that need controlled email delivery and compliance-focused communication workflows rather than a basic mailbox service.
Published Secure Gateway plans run from $50 per month for up to 5 users to $280 per month for 40 users, with 10-, 20-, and 30-user tiers at $70, $140, and $210 per month. Each listed gateway tier includes automatic SecureLine encryption, a HIPAA-compliant BAA, Microsoft 365 and Google Workspace overlay, HITRUST certification, and ticket and phone support. Secure High Volume Email starts at $99 per month for up to 9,999 emails and reaches $299 per month for 30,000–49,999 emails. These plans add full email content encryption, REST API and SMTP access, and advanced API and webhooks.
LuxSci fits teams connecting secure email to existing healthcare and business systems. Integrations include Salesforce, HubSpot, Epic, and Cerner, while REST API and webhook access supports application-driven workflows. PHI-powered segmentation and personalization, automated campaigns, templates, and a drag-and-drop builder extend the platform beyond gateway routing. Its main limitation is focus: organizations seeking a simple, low-cost mailbox provider may find the compliance and communications scope broader than needed. Teams with regulated healthcare workflows, secure delivery requirements, or high-volume messaging should find the feature set more relevant.
LuxSci pros and cons
- Where it wins
- Automatic encryption with secure portal, PGP, and S/MIME options
- HIPAA-compliant BAA, HITRUST certification, and audit trails
- Microsoft 365, Google Workspace, CRM, EHR, API, and webhook integrations
- Where it doesn't
- No free plan and a $50 monthly entry price for Secure Gateway
- Secure Gateway pricing is centered on up to 40 users
- More focused on secure communications than ordinary mailbox hosting
LuxSci fact sheet, pricing and score →
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