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Head-to-head · Research Project Management Software

SiteVault CTMS vs Advarra OnCore

  • Updated Oct 2026
  • Both researched from official sources
  • 3 checks side by side
Higher score SiteVault CTMS #4 in Research Project Management Software 9.0/10 Free plan · pricing on request Free plan✓ 2 of 3 features Visit SiteVault
Advarra OnCore #5 in Research Project Management Software 8.9/10 Pricing on request ✓ 2 of 3 features Visit Advarra OnCore

SiteVault CTMS leads on 0 checks, Advarra OnCore on 0, and 3 are even. Who comes out ahead on the 3 yes/no, price and count checks where we have data for both products. The editor score weighs everything else too.

Our verdict

  • Highest scoreSiteVault CTMS · 9.0/10
  • Free planonly SiteVault CTMS

SiteVault CTMS scores higher on our rubric for research project management software: 9.0 against 8.9 out of 10; our editors rank them #4 and #5.

SiteVault CTMS is the better fit for research sites seeking a free CTMS option. Advarra OnCore is the better fit for enterprise clinical research operations.

  • SiteVault CTMS fits best

    Research sites seeking a free CTMS option

  • Advarra OnCore fits best

    Enterprise clinical research operations

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Side by side

Feature SiteVault CTMS 9.0/10 Visit ↗ Advarra OnCore 8.9/10 Visit ↗
At a glance
Editor score 9.0 8.9
Ranking #4 in Research Project Management Software #5 in Research Project Management Software
Best for Research sites seeking a free CTMS option Enterprise clinical research operations
Pricing model Free plan + paid Paid
Starting price — —
Free plan ✓ (best) Not checked yet
Free trial — —
Deployment Cloud Cloud
Support Email, Live chat, Phone, Docs · 24/7 Email
Compliance SOC 2, ISO 27001, GDPR, HIPAA, SSO/SAML HIPAA, SSO/SAML
Integrations 5 integrations 9 integrations
Built for Small business, Mid-market, Enterprise Mid-market, Enterprise
Features SiteVault CTMS 2/3 · Advarra OnCore 2/3
Protocol management ✓ ✓
Electronic lab notebook Not checked yet Not checked yet
Milestone tracking ✓ ✓
Specs
Included team members Not checked yet Not checked yet
Included data storage Not checked yet Not checked yet
Deployment options Cloud Cloud
Our review
Pros
  • Free CTMS, eISF, and eConsent for sites with up to 20 active studies
  • Covers protocols, visits, budgets, invoicing, reconciliation, and reporting
  • Web, mobile, API, EHR, and Veeva ecosystem coverage
  • Covers protocol lifecycle, subjects, visits, financials, and close-out
  • Supports billing compliance and Medicare Coverage Analysis workflows
  • Connects EMRs, eIRB, general ledger, and Advarra applications
Cons
  • Enterprise pricing uses a contact-sales model
  • SiteVault Free is limited to 20 concurrent active studies
  • Broader financial and trial workflows may exceed smaller sites' needs
  • Pricing requires a sales conversation
  • No free plan is offered
  • Its broad scope may exceed smaller research teams' needs
Our verdict

SiteVault CTMS is a cloud-based clinical trial management system for research sites. It brings protocol, amendment, milestone, schedule-of-events, participant visit, budget, invoicing, payment reconciliation, reporting, and dashboard…

Read the review →

Advarra OnCore is a cloud clinical trial management system for academic medical centers, NCI-designated cancer centers, and health systems managing complex research operations. It brings protocol setup, activation, lifecycle management,…

Read the review →
  1. SiteVault CTMSResearch Project Management Software 9.0Free plan · pricing on request
  2. Advarra OnCoreResearch Project Management Software 8.9Pricing on request

Strengths and trade-offs

  • SiteVault CTMS — where it wins

    • Free CTMS, eISF, and eConsent for sites with up to 20 active studies
    • Covers protocols, visits, budgets, invoicing, reconciliation, and reporting
    • Web, mobile, API, EHR, and Veeva ecosystem coverage

    Where it doesn't

    • Enterprise pricing uses a contact-sales model
    • SiteVault Free is limited to 20 concurrent active studies
    • Broader financial and trial workflows may exceed smaller sites' needs

  • Advarra OnCore — where it wins

    • Covers protocol lifecycle, subjects, visits, financials, and close-out
    • Supports billing compliance and Medicare Coverage Analysis workflows
    • Connects EMRs, eIRB, general ledger, and Advarra applications

    Where it doesn't

    • Pricing requires a sales conversation
    • No free plan is offered
    • Its broad scope may exceed smaller research teams' needs

More comparisons

All research project management software comparisons → · Full ranking →

Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026

Last updated · How we research and update