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Head-to-head · Endpoint Protection Platforms

Microsoft Defender for Business vs ESET Endpoint Security

  • Updated Oct 2026
  • Both researched from official sources
  • 6 checks side by side
Higher score Microsoft Defender for Business #3 in Endpoint Protection Platforms 9.1/10 30-day trial Free trial✓ 0 of 5 features Visit site
ESET Endpoint Security #5 in Endpoint Protection Platforms 8.9/10 30-day trial Free trial✓ 5 of 5 features Visit ESET

Microsoft Defender for Business leads on 0 checks, ESET Endpoint Security on 0, and 6 are even. Who comes out ahead on the 6 yes/no, price and count checks where we have data for both products. The editor score weighs everything else too.

Our verdict

  • Highest scoreMicrosoft Defender for Business · 9.1/10
  • Free trialboth
  • Most featuresESET Endpoint Security · 5 of 5

Microsoft Defender for Business scores higher on our rubric for endpoint protection platforms: 9.1 against 8.9 out of 10; our editors rank them #3 and #5.

Microsoft Defender for Business is the better fit for small businesses wanting strong value. ESET Endpoint Security is the better fit for mixed-OS teams needing strong endpoint fundamentals.

  • Microsoft Defender for Business fits best

    Small businesses wanting strong value

  • ESET Endpoint Security fits best

    Mixed-OS teams needing strong endpoint fundamentals

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Side by side

Feature Microsoft Defender for Business 9.1/10 Visit ↗ ESET Endpoint Security 8.9/10 Visit ↗
At a glance
Editor score 9.1 8.9
Ranking #3 in Endpoint Protection Platforms #5 in Endpoint Protection Platforms
Best for Small businesses wanting strong value Mixed-OS teams needing strong endpoint fundamentals
Pricing model Paid Paid
Starting price $3/user/mo 30-day trial
Free plan — —
Free trial 30 days 30 days
Free trial length 30 days · card required 30 days · no card needed
Deployment Cloud, Mobile Cloud, Self-hosted, Desktop, Mobile
Platforms Web, Windows, macOS, iOS, Android Web, Windows, macOS, Linux, iOS, Android
Support Docs Email, Live chat, Phone, Docs
Built for Small business, Mid-market Small business, Mid-market, Enterprise
Features Microsoft Defender for Business 0/5 · ESET Endpoint Security 5/5
Behavioral protection Not checked yet ✓ (best)
Exploit blocking Not checked yet ✓ (best)
Central management console Not checked yet ✓ (best)
Device control Not checked yet ✓ (best)
Server protection Not checked yet ✓ (best)
Specs
Supported operating systems Not checked yet Not checked yet
Our review
Pros
  • Covers Windows, macOS, iOS, and Android devices
  • Combines EDR, ransomware disruption, and automated remediation
  • Integrates with Intune, SIEM, RMM, and PSA tools
  • Behavior-based ransomware protection with automated file restoration
  • Fileless-attack mitigation, exploit blocking, and memory scanning
  • Cloud or on-premises management with device and server security
Cons
  • Annual billing applies to the $3 per user monthly price
  • The plan supports up to 300 users and five devices per user
  • Server protection is an optional add-on
  • No free plan is available
  • The feature set may exceed the needs of narrowly focused teams
  • Paid plans require selecting a business security tier
Our verdict

Microsoft Defender for Business is an endpoint security solution for small and medium-sized organizations with up to 300 users. It protects Windows, macOS, iOS, and Android devices through next-generation antivirus, vulnerability…

Read the review →

ESET Endpoint Security is a paid endpoint protection platform for organizations managing business desktops, laptops, smartphones, and servers. It supports Windows, macOS, Linux, Android, and iOS, making it a practical fit for mixed-OS…

Read the review →
  1. Microsoft Defender for BusinessEndpoint Protection Platforms 9.130-day trial
  2. ESET Endpoint SecurityEndpoint Protection Platforms 8.930-day trial

Strengths and trade-offs

  • Microsoft Defender for Business — where it wins

    • Covers Windows, macOS, iOS, and Android devices
    • Combines EDR, ransomware disruption, and automated remediation
    • Integrates with Intune, SIEM, RMM, and PSA tools

    Where it doesn't

    • Annual billing applies to the $3 per user monthly price
    • The plan supports up to 300 users and five devices per user
    • Server protection is an optional add-on
  • ESET Endpoint Security — where it wins

    • Behavior-based ransomware protection with automated file restoration
    • Fileless-attack mitigation, exploit blocking, and memory scanning
    • Cloud or on-premises management with device and server security

    Where it doesn't

    • No free plan is available
    • The feature set may exceed the needs of narrowly focused teams
    • Paid plans require selecting a business security tier
  • Microsoft Defender for Business9.1/10 · 30-day trial

    Broad device coverage, EDR, and Microsoft integrations at $3 per user monthly.

    Visit siteFull verdict →
  • ESET Endpoint Security8.9/10 · 30-day trial

    A broad endpoint security suite for mixed-OS teams that need centralized control.

    Visit ESETFull verdict →

More comparisons

Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026

Last updated · How we research and update