Head-to-head · Endpoint Protection Platforms
SentinelOne Singularity Endpoint vs Microsoft Defender for Business
SentinelOne Singularity Endpoint leads on 0 checks, Microsoft Defender for Business on 0, and 6 are even. Who comes out ahead on the 6 yes/no, price and count checks where we have data for both products. The editor score weighs everything else too.
Our verdict
- Highest scoreSentinelOne Singularity Endpoint · 9.3/10
- Free trialonly Microsoft Defender for Business
- Most featuresSentinelOne Singularity Endpoint · 5 of 5
SentinelOne Singularity Endpoint scores higher on our rubric for endpoint protection platforms: 9.3 against 9.1 out of 10; our editors rank them #2 and #3.
SentinelOne Singularity Endpoint is the better fit for enterprises needing broad EDR coverage. Microsoft Defender for Business is the better fit for small businesses wanting strong value.
- SentinelOne Singularity Endpoint fits best
Enterprises needing broad EDR coverage
- Microsoft Defender for Business fits best
Small businesses wanting strong value
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Side by side
| Feature | SentinelOne Singularity Endpoint 9.3/10 Visit ↗ | Microsoft Defender for Business 9.1/10 Visit ↗ |
|---|---|---|
| At a glance | ||
| Editor score | 9.3 | 9.1 |
| Ranking | #2 in Endpoint Protection Platforms | #3 in Endpoint Protection Platforms |
| Best for | Enterprises needing broad EDR coverage | Small businesses wanting strong value |
| Pricing model | Paid | Paid |
| Starting price | $179.99/device/yr | $3/user/mo |
| Free plan | — | — |
| Free trial | — | 30 days |
| Deployment | Cloud, Self-hosted | Cloud, Mobile |
| Platforms | Web, Windows, macOS, Linux, iOS, Android | Web, Windows, macOS, iOS, Android |
| Support | Community, Docs | Docs |
| Integrations | 8 integrations | 4 integrations |
| Built for | Small business, Mid-market, Enterprise | Small business, Mid-market |
| Features SentinelOne Singularity Endpoint 5/5 · Microsoft Defender for Business 0/5 | ||
| Behavioral protection | ✓ (best) | Not checked yet |
| Exploit blocking | ✓ (best) | Not checked yet |
| Central management console | ✓ (best) | Not checked yet |
| Device control | ✓ (best) | Not checked yet |
| Server protection | ✓ (best) | Not checked yet |
| Specs | ||
| Supported operating systems | Not checked yet | Not checked yet |
| Our review | ||
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| Our verdict | SentinelOne Singularity Endpoint is an endpoint protection and detection platform for organizations managing workstations, servers, cloud workloads and mobile devices. It combines behavioral AI detection with real-time prevention for… Read the review → |
Microsoft Defender for Business is an endpoint security solution for small and medium-sized organizations with up to 300 users. It protects Windows, macOS, iOS, and Android devices through next-generation antivirus, vulnerability… Read the review → |
Strengths and trade-offs
SentinelOne Singularity Endpoint — where it wins
- Behavioral AI detects suspicious activity across endpoint, cloud and identity events
- Automated containment, remediation and rollback help limit unauthorized changes
- Supports Windows, macOS, Linux, iOS, Android, servers and cloud workloads
Where it doesn't
- Starting price is $179.99 per endpoint annually
- There is no free plan
- Annual pricing may vary by region and authorized partner terms
Microsoft Defender for Business — where it wins
- Covers Windows, macOS, iOS, and Android devices
- Combines EDR, ransomware disruption, and automated remediation
- Integrates with Intune, SIEM, RMM, and PSA tools
Where it doesn't
- Annual billing applies to the $3 per user monthly price
- The plan supports up to 300 users and five devices per user
- Server protection is an optional add-on
- SentinelOne Singularity Endpoint9.3/10 · Paid
Broad endpoint, mobile, server and cloud protection with automated response.
Visit SentinelOneFull verdict → - Microsoft Defender for Business9.1/10 · 30-day trial
Broad device coverage, EDR, and Microsoft integrations at $3 per user monthly.
Visit siteFull verdict →
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All endpoint protection platforms comparisons → · Full ranking →
Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026
Last updated · How we research and update