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Head-to-head · Endpoint Protection Platforms

Sophos Endpoint vs Microsoft Defender for Business

  • Updated Oct 2026
  • Both researched from official sources
  • 6 checks side by side
Higher score Sophos Endpoint #1 in Endpoint Protection Platforms 9.4/10 Pricing on request · 30-day trial Free trial✓ 5 of 5 features Visit Sophos
Microsoft Defender for Business #3 in Endpoint Protection Platforms 9.1/10 30-day trial Free trial✓ 0 of 5 features Visit site

Sophos Endpoint leads on 0 checks, Microsoft Defender for Business on 0, and 6 are even. Who comes out ahead on the 6 yes/no, price and count checks where we have data for both products. The editor score weighs everything else too.

Our verdict

  • Highest scoreSophos Endpoint · 9.4/10
  • Free trialboth
  • Most featuresSophos Endpoint · 5 of 5

Sophos Endpoint scores higher on our rubric for endpoint protection platforms: 9.4 against 9.1 out of 10; our editors rank them #1 and #3.

Sophos Endpoint is the better fit for teams wanting balanced endpoint protection. Microsoft Defender for Business is the better fit for small businesses wanting strong value.

  • Sophos Endpoint fits best

    Teams wanting balanced endpoint protection

  • Microsoft Defender for Business fits best

    Small businesses wanting strong value

Advertiser disclosure: iTechGuides is reader-supported. Vendors can pay for top positions in our rankings and for a place on other products' pages, and we may earn a commission when you click some links. Bought places stand at the number bought; this page and our disclosure say so. Paying vendors may get a fuller, more detailed review from our editors, and that review can change their score. How we rank.

Side by side

Feature Sophos Endpoint 9.4/10 Visit ↗ Microsoft Defender for Business 9.1/10 Visit ↗
At a glance
Editor score 9.4 9.1
Ranking #1 in Endpoint Protection Platforms #3 in Endpoint Protection Platforms
Best for Teams wanting balanced endpoint protection Small businesses wanting strong value
Pricing model Paid Paid
Starting price Pricing on request · 30-day trial $3/user/mo
Free plan — —
Free trial 30 days 30 days
Free trial length 30 days 30 days · card required
Deployment Cloud, Desktop Cloud, Mobile
Platforms Web, Windows, macOS, Linux Web, Windows, macOS, iOS, Android
Support Phone, Live chat, Tickets, Community, Docs · 24/7 Docs
Integrations 4 integrations 4 integrations
Built for Small business, Mid-market, Enterprise Small business, Mid-market
Features Sophos Endpoint 5/5 · Microsoft Defender for Business 0/5
Behavioral protection ✓ (best) Not checked yet
Exploit blocking ✓ (best) Not checked yet
Central management console ✓ (best) Not checked yet
Device control ✓ (best) Not checked yet
Server protection ✓ (best) Not checked yet
Specs
Supported operating systems Not checked yet Not checked yet
Our review
Pros
  • AI prevention, exploit mitigation, and behavioral analysis
  • Ransomware protection with file rollback and detection response
  • Centralized control across Windows, macOS, Linux, and servers
  • Covers Windows, macOS, iOS, and Android devices
  • Combines EDR, ransomware disruption, and automated remediation
  • Integrates with Intune, SIEM, RMM, and PSA tools
Cons
  • Paid plans require a personalized quote
  • There is no free plan
  • Sophos Central is gradually transitioning to Sophos Fusion
  • Annual billing applies to the $3 per user monthly price
  • The plan supports up to 300 users and five devices per user
  • Server protection is an optional add-on
Our verdict

Sophos Endpoint is a business endpoint protection and EDR product for securing desktops, laptops, servers, and other managed devices. It is positioned for small businesses, mid-market organizations, and enterprises that want prevention,…

Read the review →

Microsoft Defender for Business is an endpoint security solution for small and medium-sized organizations with up to 300 users. It protects Windows, macOS, iOS, and Android devices through next-generation antivirus, vulnerability…

Read the review →
  1. Sophos EndpointEndpoint Protection Platforms 9.4Pricing on request · 30-day trial
  2. Microsoft Defender for BusinessEndpoint Protection Platforms 9.130-day trial

Strengths and trade-offs

  • Sophos Endpoint — where it wins

    • AI prevention, exploit mitigation, and behavioral analysis
    • Ransomware protection with file rollback and detection response
    • Centralized control across Windows, macOS, Linux, and servers

    Where it doesn't

    • Paid plans require a personalized quote
    • There is no free plan
    • Sophos Central is gradually transitioning to Sophos Fusion

  • Microsoft Defender for Business — where it wins

    • Covers Windows, macOS, iOS, and Android devices
    • Combines EDR, ransomware disruption, and automated remediation
    • Integrates with Intune, SIEM, RMM, and PSA tools

    Where it doesn't

    • Annual billing applies to the $3 per user monthly price
    • The plan supports up to 300 users and five devices per user
    • Server protection is an optional add-on
  • Sophos Endpoint9.4/10 · Pricing on request · 30-day trial

    A broad endpoint and EDR suite for teams managing desktops, servers, and devices.

    Visit SophosFull verdict →
  • Microsoft Defender for Business9.1/10 · 30-day trial

    Broad device coverage, EDR, and Microsoft integrations at $3 per user monthly.

    Visit siteFull verdict →

More comparisons

All endpoint protection platforms comparisons → · Full ranking →

Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026

Last updated · How we research and update