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Head-to-head · Endpoint Protection Platforms

Microsoft Defender for Business vs Comodo Advanced Endpoint Protection

  • Updated Oct 2026
  • Both researched from official sources
  • 7 checks side by side
Higher score Microsoft Defender for Business #3 in Endpoint Protection Platforms 9.1/10 30-day trial Free trial✓ 0 of 5 features Visit site

Microsoft Defender for Business leads on 1 check, Comodo Advanced Endpoint Protection on 0, and 6 are even. Who comes out ahead on the 7 yes/no, price and count checks where we have data for both products. The editor score weighs everything else too.

Our verdict

  • Highest scoreMicrosoft Defender for Business · 9.1/10
  • Lowest starting priceMicrosoft Defender for Business · $3/user/mo
  • Free trialboth
  • Most featuresComodo Advanced Endpoint Protection · 5 of 5

Microsoft Defender for Business scores higher on our rubric for endpoint protection platforms: 9.1 against 8.6 out of 10; our editors rank them #3 and #8.

Microsoft Defender for Business is cheaper to start at $3/user/mo against $4/user/mo.

Microsoft Defender for Business is the better fit for small businesses wanting strong value. Comodo Advanced Endpoint Protection is the better fit for budget-conscious mixed-platform teams.

  • Microsoft Defender for Business fits best

    Small businesses wanting strong value

  • Comodo Advanced Endpoint Protection fits best

    Budget-conscious mixed-platform teams

Advertiser disclosure: iTechGuides is reader-supported. Vendors can pay for top positions in our rankings and for a place on other products' pages, and we may earn a commission when you click some links. Bought places stand at the number bought; this page and our disclosure say so. Paying vendors may get a fuller, more detailed review from our editors, and that review can change their score. How we rank.

Side by side

Feature Microsoft Defender for Business 9.1/10 Visit ↗ Comodo Advanced Endpoint Protection 8.6/10 Visit ↗
At a glance
Editor score 9.1 8.6
Ranking #3 in Endpoint Protection Platforms #8 in Endpoint Protection Platforms
Best for Small businesses wanting strong value Budget-conscious mixed-platform teams
Pricing model Paid Paid
Starting price $3/user/mo (best) $4/device/mo
Free plan — —
Free trial 30 days 30 days
Free trial length 30 days · card required 30 days
Deployment Cloud, Mobile Cloud, Desktop, Mobile
Platforms Web, Windows, macOS, iOS, Android Web, Windows, macOS, Linux, iOS, Android
Support Docs Email, Phone, Tickets, Community, Docs · 24/7
Integrations 4 integrations 3 integrations
Built for Small business, Mid-market Small business, Mid-market, Enterprise
Features Microsoft Defender for Business 0/5 · Comodo Advanced Endpoint Protection 5/5
Behavioral protection Not checked yet ✓ (best)
Exploit blocking Not checked yet ✓ (best)
Central management console Not checked yet ✓ (best)
Device control Not checked yet ✓ (best)
Server protection Not checked yet ✓ (best)
Specs
Supported operating systems Not checked yet Not checked yet
Our review
Pros
  • Covers Windows, macOS, iOS, and Android devices
  • Combines EDR, ransomware disruption, and automated remediation
  • Integrates with Intune, SIEM, RMM, and PSA tools
  • Covers Windows, macOS, Linux, iOS and Android endpoints
  • Automatically contains unknown files in an isolated environment
  • Includes centralized administration, device control and threat notifications
Cons
  • Annual billing applies to the $3 per user monthly price
  • The plan supports up to 300 users and five devices per user
  • Server protection is an optional add-on
  • Monthly billing is listed at $39 per device per month
  • Advanced features may require more security-policy administration
  • The plan lineup is presented under the same Premium name
Our verdict

Microsoft Defender for Business is an endpoint security solution for small and medium-sized organizations with up to 300 users. It protects Windows, macOS, iOS, and Android devices through next-generation antivirus, vulnerability…

Read the review →

Comodo Advanced Endpoint Protection is an endpoint security platform for small and midsize businesses and enterprise environments. It combines antivirus, firewall, host intrusion prevention, behavioral analysis, file reputation, automatic…

Read the review →
  1. Microsoft Defender for BusinessEndpoint Protection Platforms 9.130-day trial
  2. Comodo Advanced Endpoint ProtectionEndpoint Protection Platforms 8.630-day trial

Strengths and trade-offs

  • Microsoft Defender for Business — where it wins

    • Covers Windows, macOS, iOS, and Android devices
    • Combines EDR, ransomware disruption, and automated remediation
    • Integrates with Intune, SIEM, RMM, and PSA tools

    Where it doesn't

    • Annual billing applies to the $3 per user monthly price
    • The plan supports up to 300 users and five devices per user
    • Server protection is an optional add-on
  • Comodo Advanced Endpoint Protection — where it wins

    • Covers Windows, macOS, Linux, iOS and Android endpoints
    • Automatically contains unknown files in an isolated environment
    • Includes centralized administration, device control and threat notifications

    Where it doesn't

    • Monthly billing is listed at $39 per device per month
    • Advanced features may require more security-policy administration
    • The plan lineup is presented under the same Premium name
  • Microsoft Defender for Business9.1/10 · 30-day trial

    Broad device coverage, EDR, and Microsoft integrations at $3 per user monthly.

    Visit siteFull verdict →
  • Comodo Advanced Endpoint Protection8.6/10 · 30-day trial

    Broad endpoint coverage and strong containment at a low annual per-device price.

    Visit ComodoFull verdict →

More comparisons

Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026

Last updated · How we research and update