Prisma AIRS

Paid#10 of 30 in LLM Security ToolsAI Agent Security Software

Prisma AIRS: A broad AI security platform for runtime inspection, guardrails and gateway enforcement. Ranked #10 of 30 in LLM Security Tools by our editors (8.4/10); pricing: Pricing on request; best for mature enterprises needing AI gateway controls.

8.4/10★★★★☆Editor score

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At a glance

• Editor score
  8.4 / 10
• Pricing
  Pricing on request
• Best for
  Mature enterprises needing AI gateway controls
• Prompt injection defense
  Yes
• Founded
  2005 · Santa Clara, California, United States
• Facts checked
  21 Sep 2026

• Where it wins

  • Blocks prompt injection and detects sensitive-data or credential leakage
  • Checks outputs for malicious code, URLs, toxicity and grounding
  • Supports SaaS, hybrid and private-cloud deployment models

• Where it doesn't

  • Pricing requires a sales conversation
  • Its broad scope may exceed focused AI security needs
  • Deployment spans multiple components and policy controls

Our verdict on Prisma AIRS

Prisma AIRS is Palo Alto Networks’ AI security platform for enterprises deploying AI applications, agents and models. It focuses on live protection across prompts, responses and data flows, with AI Runtime Security, API-based threat scanning and AI Gateway visibility. Mature organizations seeking centralized inspection and policy enforcement across AI workloads are the clearest fit, particularly those operating applications across web, API and self-hosted environments.

Its standout capability is the breadth of runtime controls. Prisma AIRS detects and blocks prompt injection, identifies sensitive data and PII leakage, protects credentials and confidential information, and scans outputs for malicious code and URLs. It also applies toxic-content blocking, custom topic guardrails and contextual grounding checks. Together, these controls cover both inbound prompts and outbound responses, while the AI Gateway adds visibility and policy enforcement for application traffic. Teams that need several layers of AI-specific inspection in one platform should find this scope relevant.

Platform fit is another strength. Prisma AIRS integrates with Microsoft Foundry, Microsoft Copilot Studio, AWS Bedrock, GCP Vertex AI and VoiceFlow. Palo Alto Networks documents cloud-managed services, private-cloud infrastructure and hybrid deployment, including a private-cloud option for the AI Runtime Firewall. Licensing is available through BYOL and consumption-based models, with pricing handled through contact sales. Choose Prisma AIRS when runtime controls, gateway enforcement and deployment flexibility matter together; teams seeking a narrowly focused tool or a publicly listed fixed price should consider alternatives.

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Prisma AIRS pricing

Prisma AIRS fact sheet

Prisma AIRS integrations

Prisma AIRS lists 5 integrations on its own site.

• Microsoft Foundry
• Microsoft Copilot Studio
• AWS Bedrock
• GCP Vertex AI
• VoiceFlow

Alternatives to Prisma AIRS

• Guardrails AIA broad open-source toolkit for runtime LLM validation, policy enforcement, and risk detection.9.3
• LGLLM GuardA self-hosted toolkit for scanning prompts, outputs, PII, secrets, and LLM risks.9.2
• NVIDIA NeMo GuardrailsA broad, self-hosted toolkit for controlling inputs, outputs, tools, and AI-agent behavior.9.1

See all Prisma AIRS alternatives →

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Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026

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Last updated 7 Oct 2026 · How we research and update