OpenClinica
OpenClinica: A configurable clinical data platform with EDC, consent, randomization, and analytics. Ranked #18 of 20 in Research Administration Software by our editors (6.5/10); pricing: 30-day trial; best for clinical studies needing configurable data capture.
At a glance
- Editor score6.5 / 10
- Pricing30-day trial
- Best forClinical studies needing configurable data capture
- Free planNo
- Facts checked21 Sep 2026
Where it wins
- Covers EDC, consent, randomization, EHR integration, and analytics
- Drag-and-drop study builder with templated CRFs and automated workflows
- REST API, audit trails, and role-based permissions support controlled data exchange
Where it doesn't
- No free plan is offered
- Launch is limited to EDC, 150 participants, and 3 sites
- Advanced capabilities and broader modules require higher-tier plans
Our verdict on OpenClinica
OpenClinica is a cloud-based eClinical platform for academic researchers, contract research organizations, clinical research sites, and study teams. Its core focus is clinical data management rather than grant administration. The platform combines electronic data capture and electronic case report forms with a drag-and-drop study builder, templated CRFs, real-time validation, automated workflows, electronic consent, patient reporting, randomization, and treatment allocation. It is available through web and API access, with EHR-to-EDC integration for data exchange.
The published plans show a tiered structure that expands from focused data capture to broader study operations. Launch provides EDC, self-service study setup, email notifications, and self-service support, with capacity for up to 150 participants and 3 sites. Core adds reporting and analytics, a dedicated isolated EDC, role-based permissions, workflows, SMS, full API access, a 24/5 helpdesk, and a dedicated customer success manager. Advanced adds one module, analytics without data limits, MFA, SSO, user-level audit trails, and professional services. Enterprise & Academic adds all modules, multi-study support, enterprise analytics, expanded identity controls, and custom support packages. A 30-day trial is available, but there is no free plan.
OpenClinica is a strong fit when a study needs configurable forms, controlled workflows, participant-facing consent or outcome collection, and programmatic data exchange. Its audit trails, permissions, validation, and reporting features also suit teams that need structured oversight across clinical studies. The main trade-off is scope: this is specialized clinical-trial software, not a general research administration system. Smaller studies may find Launch appropriate if EDC is the priority, while teams needing analytics, integrations, advanced identity controls, or multiple modules should consider Core, Advanced, or Enterprise & Academic. Organizations focused mainly on grants, budgets, or broader institutional research administration should choose a more specialized alternative.
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OpenClinica pricing
All 4 OpenClinica plans and prices →
OpenClinica fact sheet
| Free plan | No |
|---|---|
| Paid from | Not verified |
| Grant lifecycle | Not verified |
| Proposal management | Not verified |
| Award management | Not verified |
| Compliance workflows | Yes |
| Agreement management | Not verified |
| Budget tracking | Not verified |
| API access | Yes |
| Free trial | 30 days |
| Deployment | Cloud |
| Platforms | Web |
| Compliance & security | SOC 2, ISO 27001, GDPR, HIPAA |
| Support | Email, Phone, Tickets, Docs |
| Built for | Small business, Mid-market, Enterprise (editorial estimate) |
| Integrations | 1 integrations: EHR systems |
| Pricing | 30-day trial (source) |
| Website | openclinica.com |
| Facts checked | 21 Sep 2026 |
OpenClinica integrations
OpenClinica lists 1 integrations on its own site.
- EHR systems
Alternatives to OpenClinica
- Fibi Research Administration SoftwareEnd-to-end research administration with configurable workflows, compliance, reporting, and integrations.9.4
- Streamlyne ResearchA broad research administration suite for universities managing complex workflows.9.2
- Kuali ResearchA broad research administration suite for institutions with complex compliance workflows.9.0
See all OpenClinica alternatives →
Also Ranked In
OpenClinica is ranked in 3 of our directories.
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Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026
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