DisEASE

At a glance

• Editor score
  7.4 / 10
• Pricing
  Pricing on request
• Best for
  Teams prioritizing medication selection and safety
• Differential diagnosis
  No
• Facts checked
  14 Nov 2026

• Where it wins

  • Deterministic medication rankings use pharmacist-verified, traceable rules.
  • Safety screening flags concerns across structured patient information.
  • Epic access uses a read-only SMART on FHIR integration.

• Where it doesn't

  • Supports type 2 diabetes, hypertension, and heart failure only.
  • Does not provide differential diagnosis.
  • Epic integration is read-only, and pricing requires a sales discussion.

Our verdict on DisEASE

DisEASE is clinical decision support software for licensed clinicians managing adults with chronic disease. It focuses on medication selection and safety rather than differential diagnosis, making it relevant to teams that want structured treatment guidance for type 2 diabetes, hypertension, and heart failure. Clinicians enter patient information such as vitals, labs, comorbidities, allergies, and current therapies; the system ranks medication options and provides safety alerts. Its outputs are intended to support, not replace, clinical judgment.

A key distinction is the separation between deterministic scoring and the AI assistant. Medication rankings come from a pharmacist-verified rules engine, with trace logs showing which rules fired. The assistant can explain the rankings and retrieve cited evidence, but it does not change scores or add recommendations. DisEASE also drafts assessment-and-plan clinical notes. This combination suits teams that value an explainable medication workflow; it is less suited to clinicians looking for a broad diagnostic assistant or recommendations beyond the conditions the product supports.

DisEASE is available in a browser and can be launched from Epic through a read-only SMART on FHIR integration. That offers a defined path for organizations using Epic, while the read-only connection does not provide write-back. The product is cloud deployed, lists GDPR compliance, and offers email support. Its pricing model is contact sales, with subscription renewal documented, so organizations should discuss fit and commercial terms directly. Teams seeking focused, traceable medication decision support may find its scope appropriate; those needing differential diagnosis, broader condition coverage, or an Epic workflow that writes data back should consider alternatives.

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DisEASE pricing

DisEASE fact sheet

DisEASE integrations

DisEASE lists 1 integrations on its own site.

• Epic

See all DisEASE integrations →

Alternatives to DisEASE

• UEUpToDate Expert AIPatient-contextualized clinical answers with differential refinement and cited UpToDate topics.9.2
• CClinicalKey AIConversational clinical decision support grounded in cited, refreshed medical content.9.0
• IInfermedicaA triage-focused clinical AI platform for symptom assessment, intake, and care routing.8.8

See all DisEASE alternatives →

Featured on iTechGuides

DisEASE is listed in our AI Clinical Decision Support Software directory. Add the badge to your site — it links back to this page.

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Reviewed by iTechGuides Editors · Editorial team · Updated Nov 2026

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Last updated 14 Nov 2026 · How we research and update