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Head-to-head · Clinical Trial Management

SiteVault CTMS vs CRIO Site CTMS

  • Updated Oct 2026
  • Both researched from official sources
  • 6 checks side by side
Higher score SiteVault CTMS #2 in Clinical Trial Management 9.0/10 Free plan · pricing on request Free plan✓ 0 of 5 features Visit SiteVault
CRIO Site CTMS #5 in Clinical Trial Management 8.6/10 Pricing on request ✓ 5 of 5 features Visit CRIO

SiteVault CTMS leads on 1 check, CRIO Site CTMS on 0, and 5 are even. Who comes out ahead on the 6 yes/no, price and count checks where we have data for both products. The editor score weighs everything else too.

Our verdict

  • Highest scoreSiteVault CTMS · 9.0/10
  • Free planonly SiteVault CTMS
  • Most featuresCRIO Site CTMS · 5 of 5

SiteVault CTMS scores higher on our rubric for clinical trial management: 9.0 against 8.6 out of 10; our editors rank them #2 and #5.

SiteVault CTMS offers free plan; CRIO Site CTMS doesn't.

SiteVault CTMS is the better fit for research sites seeking a free, integrated CTMS. CRIO Site CTMS is the better fit for sites managing recruitment, visits, and payments.

  • SiteVault CTMS fits best

    Research sites seeking a free, integrated CTMS

  • CRIO Site CTMS fits best

    Sites managing recruitment, visits, and payments

Advertiser disclosure: iTechGuides is reader-supported. Vendors can pay for top positions in our rankings and for a place on other products' pages, and we may earn a commission when you click some links. Bought places stand at the number bought; this page and our disclosure say so. Paying vendors may get a fuller, more detailed review from our editors, and that review can change their score. How we rank.

Side by side

Feature SiteVault CTMS 9.0/10 Visit ↗ CRIO Site CTMS 8.6/10 Visit ↗
At a glance
Editor score 9.0 8.6
Ranking #2 in Clinical Trial Management #5 in Clinical Trial Management
Best for Research sites seeking a free, integrated CTMS Sites managing recruitment, visits, and payments
Pricing model Free plan + paid Paid
Starting price — Pricing on request
Free plan ✓ (best) —
Free trial — —
Deployment Cloud Cloud
Platforms Web, iOS, Android Web
Support Email, Live chat, Phone, Docs · 24/7 Email, Phone · 24/7
Compliance SOC 2, ISO 27001, GDPR, HIPAA, SSO/SAML SOC 2, ISO 27001, GDPR, HIPAA
Integrations 5 integrations 2 integrations
Built for Small business, Mid-market, Enterprise Small business, Mid-market, Enterprise
Features SiteVault CTMS 0/5 · CRIO Site CTMS 5/5
Site management Not checked yet ✓ (best)
Subject enrollment tracking Not checked yet ✓ (best)
Monitoring & visits Not checked yet ✓ (best)
Budget & payments Not checked yet ✓ (best)
Reporting dashboards Not checked yet ✓ (best)
Specs
Deployment Cloud Cloud
Included users Not checked yet Not checked yet
Our review
Pros
  • Free CTMS, eISF, and eConsent for up to 20 active studies
  • Protocol, visits, budgets, invoicing, reconciliation, and dashboards in one system
  • Web, iOS, Android, API, EHR, and Veeva Clinical Platform connectivity
  • Combines patient lead capture, screening, and visit scheduling
  • Tracks visit-level receivables, stipends, payables, and invoices
  • Includes eConsent, eSource workflows, and customizable reporting
Cons
  • SiteVault Free is limited to 20 concurrent active studies
  • Enterprise pricing requires contacting sales
  • Advanced API, SSO, and dedicated account management require Enterprise
  • Pricing requires a demo rather than published plan details
  • Integrations listed are limited to CRIO eSource and Dash Solutions
  • The product is focused on clinical research site operations
Our verdict

SiteVault CTMS is a cloud clinical trial management system for research sites. It brings protocol, amendment, milestone, schedule-of-events, participant visit, and procedure management into one workspace. Financial controls cover study…

Read the review →

CRIO Site CTMS is a cloud clinical trial management system for research sites coordinating participant recruitment, visits, and study finances. Its workflows cover a patient database and feasibility search, website lead capture, patient…

Read the review →
  1. SiteVault CTMSClinical Trial Management 9.0Free plan · pricing on request
  2. CRIO Site CTMSClinical Trial Management 8.6Pricing on request

Strengths and trade-offs

  • SiteVault CTMS — where it wins

    • Free CTMS, eISF, and eConsent for up to 20 active studies
    • Protocol, visits, budgets, invoicing, reconciliation, and dashboards in one system
    • Web, iOS, Android, API, EHR, and Veeva Clinical Platform connectivity

    Where it doesn't

    • SiteVault Free is limited to 20 concurrent active studies
    • Enterprise pricing requires contacting sales
    • Advanced API, SSO, and dedicated account management require Enterprise
  • CRIO Site CTMS — where it wins

    • Combines patient lead capture, screening, and visit scheduling
    • Tracks visit-level receivables, stipends, payables, and invoices
    • Includes eConsent, eSource workflows, and customizable reporting

    Where it doesn't

    • Pricing requires a demo rather than published plan details
    • Integrations listed are limited to CRIO eSource and Dash Solutions
    • The product is focused on clinical research site operations
  • SiteVault CTMS9.0/10 · Free plan · pricing on request

    A free-to-start CTMS that unifies site operations, finances, documents, and consent.

    Visit SiteVaultFull verdict →
  • CRIO Site CTMS8.6/10 · Pricing on request

    A site-focused CTMS connecting recruitment, visit workflows, payments, and reporting.

    Visit CRIOFull verdict →

More comparisons

Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026

Last updated · How we research and update