Head-to-head · Clinical Trial Management
SiteVault CTMS vs CRIO Site CTMS
SiteVault CTMS leads on 1 check, CRIO Site CTMS on 0, and 5 are even. Who comes out ahead on the 6 yes/no, price and count checks where we have data for both products. The editor score weighs everything else too.
Our verdict
- Highest scoreSiteVault CTMS · 9.0/10
- Free planonly SiteVault CTMS
- Most featuresCRIO Site CTMS · 5 of 5
SiteVault CTMS scores higher on our rubric for clinical trial management: 9.0 against 8.6 out of 10; our editors rank them #2 and #5.
SiteVault CTMS offers free plan; CRIO Site CTMS doesn't.
SiteVault CTMS is the better fit for research sites seeking a free, integrated CTMS. CRIO Site CTMS is the better fit for sites managing recruitment, visits, and payments.
- SiteVault CTMS fits best
Research sites seeking a free, integrated CTMS
- CRIO Site CTMS fits best
Sites managing recruitment, visits, and payments
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Side by side
| Feature | SiteVault CTMS 9.0/10 Visit ↗ | CRIO Site CTMS 8.6/10 Visit ↗ |
|---|---|---|
| At a glance | ||
| Editor score | 9.0 | 8.6 |
| Ranking | #2 in Clinical Trial Management | #5 in Clinical Trial Management |
| Best for | Research sites seeking a free, integrated CTMS | Sites managing recruitment, visits, and payments |
| Pricing model | Free plan + paid | Paid |
| Starting price | — | Pricing on request |
| Free plan | ✓ (best) | — |
| Free trial | — | — |
| Deployment | Cloud | Cloud |
| Platforms | Web, iOS, Android | Web |
| Support | Email, Live chat, Phone, Docs · 24/7 | Email, Phone · 24/7 |
| Compliance | SOC 2, ISO 27001, GDPR, HIPAA, SSO/SAML | SOC 2, ISO 27001, GDPR, HIPAA |
| Integrations | 5 integrations | 2 integrations |
| Built for | Small business, Mid-market, Enterprise | Small business, Mid-market, Enterprise |
| Features SiteVault CTMS 0/5 · CRIO Site CTMS 5/5 | ||
| Site management | Not checked yet | ✓ (best) |
| Subject enrollment tracking | Not checked yet | ✓ (best) |
| Monitoring & visits | Not checked yet | ✓ (best) |
| Budget & payments | Not checked yet | ✓ (best) |
| Reporting dashboards | Not checked yet | ✓ (best) |
| Specs | ||
| Deployment | Cloud | Cloud |
| Included users | Not checked yet | Not checked yet |
| Our review | ||
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| Cons |
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| Our verdict | SiteVault CTMS is a cloud clinical trial management system for research sites. It brings protocol, amendment, milestone, schedule-of-events, participant visit, and procedure management into one workspace. Financial controls cover study… Read the review → |
CRIO Site CTMS is a cloud clinical trial management system for research sites coordinating participant recruitment, visits, and study finances. Its workflows cover a patient database and feasibility search, website lead capture, patient… Read the review → |
Strengths and trade-offs
SiteVault CTMS — where it wins
- Free CTMS, eISF, and eConsent for up to 20 active studies
- Protocol, visits, budgets, invoicing, reconciliation, and dashboards in one system
- Web, iOS, Android, API, EHR, and Veeva Clinical Platform connectivity
Where it doesn't
- SiteVault Free is limited to 20 concurrent active studies
- Enterprise pricing requires contacting sales
- Advanced API, SSO, and dedicated account management require Enterprise
CRIO Site CTMS — where it wins
- Combines patient lead capture, screening, and visit scheduling
- Tracks visit-level receivables, stipends, payables, and invoices
- Includes eConsent, eSource workflows, and customizable reporting
Where it doesn't
- Pricing requires a demo rather than published plan details
- Integrations listed are limited to CRIO eSource and Dash Solutions
- The product is focused on clinical research site operations
- SiteVault CTMS9.0/10 · Free plan · pricing on request
A free-to-start CTMS that unifies site operations, finances, documents, and consent.
Visit SiteVaultFull verdict → - CRIO Site CTMS8.6/10 · Pricing on request
A site-focused CTMS connecting recruitment, visit workflows, payments, and reporting.
Visit CRIOFull verdict →
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All clinical trial management comparisons → · Full ranking →
Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026
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