Oracle Clinical One Data Collection vs OpenClinica

Oracle Clinical One Data Collection9.1Visit OpenClinica9.0Visit

Higher score Oracle Clinical One Data Collection #2 in Electronic Data Capture Software 9.1/10 Pricing on request ✓ 3 of 4 features Visit Oracle

vs

OpenClinica #3 in Electronic Data Capture Software 9.0/10 30-day trial Free trial✓ 0 of 4 features Visit OpenClinica

• Oracle Clinical One Data Collection fits best

  Clinical teams integrating data across multiple sources

• OpenClinica fits best

  Teams seeking EDC plus consent and trial workflows

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Side by side

Feature	Oracle Clinical One Data Collection 9.1/10 Visit ↗	OpenClinica 9.0/10 Visit ↗
At a glance
Editor score	9.1	9.0
Ranking	#2 in Electronic Data Capture Software	#3 in Electronic Data Capture Software
Best for	Clinical teams integrating data across multiple sources	Teams seeking EDC plus consent and trial workflows
Pricing model	Paid	Paid
Starting price	Pricing on request	—
Free plan	—	—
Free trial	—	30 days
Deployment	Cloud	Cloud
Platforms	Web	Web
Support	Live chat, Tickets, Docs	Email, Phone, Tickets, Docs
Compliance	SOC 2, ISO 27001, HIPAA	SOC 2, ISO 27001, GDPR, HIPAA
Integrations	9 integrations	1 integrations
Built for	Mid-market, Enterprise	Small business, Mid-market, Enterprise
Features Oracle Clinical One Data Collection 3/4 · OpenClinica 0/4
ePRO support	✓ (best)	Not checked yet
Audit trail	✓ (best)	Not checked yet
Data validation checks	✓ (best)	Not checked yet
Offline data entry	Not checked yet	Not checked yet
Specs
Regulatory compliance	ISO/IEC 27001; HIPAA; SOC 2	Not checked yet
Deployment	Cloud	Not checked yet
Our review
Pros	Collects data from EHRs, laboratories, and patient applications Supports configurable forms, validation rules, and automated queries Includes audit history, source verification, and subject/data locking	Combines EDC with eConsent, eCOA, randomization, and EHR integration Validation, workflows, audit trails, and role-based permissions support controlled studies REST API, analytics, and dashboards support programmatic exchange and trial reporting
Cons	Pricing requires contacting Oracle sales No free plan is offered Offline data entry is not verified in the product documentation	Launch limits studies to 150 participants and 3 sites Advanced capabilities depend on higher-tier plans or add-on modules Designed for clinical trials rather than grant-administration workflows
Our verdict	Oracle Clinical One Data Collection is a cloud service for contract research organizations, research sites, and clinical research teams managing trial data. It is designed for organizations that need to collect information from electronic… Read the review →	OpenClinica is a cloud-based electronic data capture and eClinical platform for academic researchers, clinical research organizations, contract research organizations, and clinical research sites. Its core tools include electronic case… Read the review →

Strengths and trade-offs

• Oracle Clinical One Data Collection — where it wins

  • Collects data from EHRs, laboratories, and patient applications
  • Supports configurable forms, validation rules, and automated queries
  • Includes audit history, source verification, and subject/data locking

  Where it doesn't

  • Pricing requires contacting Oracle sales
  • No free plan is offered
  • Offline data entry is not verified in the product documentation

• OpenClinica — where it wins

  • Combines EDC with eConsent, eCOA, randomization, and EHR integration
  • Validation, workflows, audit trails, and role-based permissions support controlled studies
  • REST API, analytics, and dashboards support programmatic exchange and trial reporting

  Where it doesn't

  • Launch limits studies to 150 participants and 3 sites
  • Advanced capabilities depend on higher-tier plans or add-on modules
  • Designed for clinical trials rather than grant-administration workflows

• Oracle Clinical One Data Collection9.1/10 · Pricing on request

  Connects clinical data sources with configurable capture, validation, and audit history.

  Visit OracleFull verdict →
• OpenClinica9.0/10 · 30-day trial

  A cloud EDC suite that adds consent, outcomes, randomization, analytics, and API-based exchange.

  Visit OpenClinicaFull verdict →