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NFL Week 4 runs from Thursday, Oct. 1 through Monday, Oct. 5, 2026. The five featured games below include exact U.S. kickoff times, networks, records entering the week and the injury news most likely to affect the matchups.
Week 4 schedule at a glance
The official schedule has 14 games on Sunday, Oct. 4, plus Steelers-Browns on Thursday night and Falcons-Saints on Monday night. All times below are Eastern Time.
| Game | Kickoff | U.S. network |
|---|---|---|
| Colts at Commanders | Sunday, Oct. 4, 9:30 a.m. | NFL Network |
| Patriots at Bills | Sunday, Oct. 4, 1 p.m. | CBS |
| Rams at Eagles | Sunday, Oct. 4, 1 p.m. | FOX |
| Chiefs at Raiders | Sunday, Oct. 4, 4:25 p.m. | CBS |
| Lions at Panthers | Sunday, Oct. 4, 8:20 p.m. | NBC |
1. Kansas City Chiefs at Las Vegas Raiders
Sunday, Oct. 4, 4:25 p.m. ET — CBS
Why it matters
This is the clearest record-driven game of Week 4. The Raiders and Chiefs are both 3-0, so the winner takes an early lead in the AFC West race. It also puts Patrick Mahomes and Kansas City’s new rushing weapon, Kenneth Walker III, in the same spotlight as an unbeaten Las Vegas team that has exceeded preseason expectations.
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- Wilson The Duke NFL Replica Football - Official Size, Brown
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- REPLICA STYLE: Built to get as close as we can to the real Duke delivering a similar look and performance, and updated with the red, silver, and blue NFL Shield
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- COMFORT CONSTRUCTION: A thicker 1.2mm layer of EVA foam underneath outer cover giving the ball a softer grip and feel
What to watch
The result should establish which team has the stronger early claim in the division. Because both clubs are unbeaten, this is the best choice if you want the highest-stakes game in the late-afternoon window.
2. New England Patriots at Buffalo Bills
Sunday, Oct. 4, 1 p.m. ET — CBS
Records and stakes
Buffalo enters at 3-0, while New England is 1-2 in the published standings. The matchup has straightforward AFC East importance, although New England’s slow start reduced some of its preseason appeal.
Injury watch
- Patriots defensive tackle Christian Barmore — out.
- Patriots cornerback Christian Gonzalez — out.
- Bills defensive lineman T.J. Sanders — doubtful.
- Bills running back Ray Davis — questionable.
- Bills cornerback Christian Benford — questionable.
The listed absences on New England’s defense and Buffalo’s uncertain availability at several positions make the final injury report particularly important before kickoff.
Rank #2
- Wilson NFL Super Grip Composite Football - Official Size, Brown
- SUPERIOR FEEL: Designed for the optimal balance between softness and toughness, the soft composite material enhances the natural feel of the ball, allowing for better handling and precision
- NFL LACING: The classic style laces you know for a trusted game feel
- AIR RETENTION: A Pressure Lock Bladder helps keep your ball fully inflated for longer with less time spent pumping and more time playing
- NFL AUTHENTICITY: Wilson is the Official Football of the NFL and trusted by the world’s best athletes for over 100 years
3. Indianapolis Colts at Washington Commanders
Sunday, Oct. 4, 9:30 a.m. ET — NFL Network, Tottenham Hotspur Stadium, London
The Tool Desk
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This is Week 4’s London game and the earliest kickoff for U.S. viewers. Both Indianapolis and Washington are listed at 1-2 entering the week, so the game offers each team a chance to move back toward .500 in a standalone international setting.
The quarterback question
Commanders quarterback Jayden Daniels is out with a left-elbow injury. Washington wide receiver Terry McLaurin is questionable because of a hamstring issue. Daniels’ absence makes Washington’s replacement-quarterback plan the central tactical question of the matchup.
Rank #3
- Wilson The Duke NFL Game Football - Official Size, Brown
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4. Los Angeles Rams at Philadelphia Eagles
Sunday, Oct. 4, 1 p.m. ET — FOX
Why it belongs on the list
Philadelphia is 2-1 through Week 3, while the Rams enter at 1-2. That gives the Eagles an opportunity to strengthen their early NFC East position against a Los Angeles team trying to even its record.
Best viewing angle
With a 1 p.m. FOX window, Rams-Eagles is the afternoon NFC matchup to choose if you want a divisional-position test without waiting for the late game. The contrast in records supplies the clearest storyline: Philadelphia is protecting an early edge, and Los Angeles is attempting to erase a slow start.
5. Detroit Lions at Carolina Panthers
Sunday, Oct. 4, 8:20 p.m. ET — NBC (Sunday Night Football)
Rank #4
- Wilson NFL MVP Football - Official Size, Brown
- SIGNATURE LOOK: Classic design inspired by NFL legends—built for players of all ages chasing their own MVP moments
- SOFTNESS & DURABILITY: Soft composite leather cover offers soft grip making for easier catches for all abilities
- AIR RETENTION: A Pressure Lock Bladder helps keep your ball fully inflated for longer with less time spent pumping and more time playing
- NFL AUTHENTICITY: Wilson is the Official Football of the NFL and trusted by the world’s best athletes for over 100 years
Why it matters
Detroit is 2-1 and Carolina is 1-2 through Week 3. The Lions arrive above .500, while the Panthers are trying to recover, creating a meaningful late-window test for both teams.
Why watch in prime time
NBC gives this matchup the week’s standalone Sunday-night broadcast. It is the best option for viewers who want one nationally presented game after the afternoon schedule ends rather than a choice among overlapping regional windows.
Independent reader supportYour contribution helps us test, update, and keep practical guides available for everyone.Other Week 4 games
The rest of the slate is:
- Steelers at Browns — Thursday, Oct. 1, Prime Video
- Titans at Ravens
- Jets at Bears
- Jaguars at Bengals
- Cowboys at Texans
- Cardinals at Giants
- Packers at Buccaneers
- Dolphins at Vikings
- Broncos at 49ers
- Chargers at Seahawks
- Falcons at Saints — Monday, Oct. 5, ESPN
The listed Sunday games are scheduled for Oct. 4; the official schedule provides the kickoff times and U.S. network assignments for the full slate.
Best Value
- Wilson NFL Super Grip Composite Football - Junior Size, Brown
- SUPERIOR FEEL: Designed for the optimal balance between softness and toughness, the soft composite material enhances the natural feel of the ball, allowing for better handling and precision
- NFL LACING: The classic style laces you know for a trusted game feel
- AIR RETENTION: A Pressure Lock Bladder helps keep your ball fully inflated for longer with less time spent pumping and more time playing
- NFL AUTHENTICITY: Wilson is the Official Football of the NFL and trusted by the world’s best athletes for over 100 years
How to choose your Week 4 viewing plan
- Want the biggest standings hook? Start with Chiefs-Raiders at 4:25 p.m. ET.
- Prefer an early game? Colts-Commanders begins at 9:30 a.m. ET from London.
- Want injury-driven uncertainty? Patriots-Bills has five notable listed statuses, including two Patriots players ruled out.
- Need an afternoon NFC matchup? Rams-Eagles is on FOX at 1 p.m. ET.
- Want a single Sunday-night broadcast? Lions-Panthers starts at 8:20 p.m. ET on NBC.
Injury designations can change before kickoff, so recheck the NFL’s official injury listings on game day, especially for Patriots-Bills and Colts-Commanders.
For one game, choose Chiefs-Raiders: it combines the only unbeaten-versus-unbeaten matchup with a late national window. The London game is the week’s most unusual setting, while Patriots-Bills carries the strongest immediate injury uncertainty.
Quick Recap
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