Case It!
Case It!: A free, wide-ranging molecular biology lab simulator for classroom case work. Ranked #7 of 24 in Biology Learning Software by our editors (6.9/10); pricing: Free plan; best for free molecular biology case-based labs.
At a glance
- Editor score6.9 / 10
- PricingFree plan
- Best forFree molecular biology case-based labs
- Free planYes
- Paid fromNone
- Biology simulationsYes
- Facts checked21 Sep 2026
Where it wins
- Covers sequence analysis, PCR, electrophoresis, blotting and ELISA
- Includes CRISPR, vaccines, disease cases, phylogenetics and forensics
- Connects with NCBI tools, MEGA and MABL for analysis workflows
Where it doesn't
- The primary application is Windows software
- Mac use requires compatibility software or a virtual machine
- The mobile version includes selected cases rather than the full simulation
Our verdict on Case It!
Case It! is a free educational molecular biology simulation project for students and instructors. Its downloadable software presents case-based exercises across DNA and protein sequence analysis, PCR, restriction digestion, electrophoresis, blotting, ELISA, microarrays, CRISPR, mRNA vaccines, phylogenetics, forensics, and genetic or infectious diseases. It suits biology courses that need virtual lab activities tied to realistic research questions rather than a single narrow simulation.
The main strength is breadth. Learners can move from sequence alignment and mutation analysis to simulated wet-lab procedures, then build phylogenetic trees or examine disease-focused cases. The software also connects with NCBI BLAST, Genome Data Viewer, dbSNP, Structure, MEGA, and MABL, giving instructors a wider analysis workflow to incorporate into teaching. Mobile case scenarios add screen-capture videos and selected browser-accessible activities, while assessment tools are part of the product’s category capabilities.
Platform choice matters for adoption. The primary application is Windows software, and Mac users need additional compatibility software or a virtual machine. Case It Mobile provides selected cases, not the full simulation, so it is better viewed as a supplementary access route than a replacement for the desktop application. Educators seeking a broad, free resource for molecular biology case work should consider Case It!, especially when Windows access is available. Courses requiring a fully browser-based experience across the complete simulation library should choose a different tool.
Case It! pricing
All 1 Case It! plans and prices →
Case It! fact sheet
| Free plan | Yes |
|---|---|
| Paid from | None |
| Virtual labs | Yes |
| Biology simulations | Yes |
| 3D biology models | Not verified |
| Assessment tools | Yes |
| Teacher tools | Not verified |
| Primary learner level | Mixed |
| Supported platforms | Mixed |
| Deployment | Desktop, Mobile, Browser extension |
| Platforms | Web, Windows, macOS |
| Support | Email, Docs |
| Built for | Small business, Mid-market, Enterprise (editorial estimate) |
| Integrations | 6 integrations: NCBI BLAST, NCBI Genome Data Viewer, NCBI dbSNP, NCBI Structure, MEGA, MABL |
| Pricing | Free plan (source) |
| Website | caseitproject.org |
| Facts checked | 21 Sep 2026 |
Case It! integrations
Case It! lists 6 integrations on its own site.
- NCBI BLAST
- NCBI Genome Data Viewer
- NCBI dbSNP
- NCBI Structure
- MEGA
- MABL
Alternatives to Case It!
- HHMI BioInteractiveA broad, free web library for biology lessons, activities, labs, simulations, and assessment.9.0
- LabXchangeA structured, free option for science learning, practice, and educator-led classes.8.2
- Biology Labs OnlineA free web suite for structured biology experiments, analysis, and assignments.7.7
See all Case It! alternatives →
Case It! vs the competition
- Case It! vs HHMI BioInteractive
- Case It! vs LabXchange
- Case It! vs Biology Labs Online
- Case It! vs BioDigital Human
- Case It! vs Achieve for Biology
- Case It! vs PraxiLabs
Compare Case It! with any tool side by side →
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Reviewed by iTechGuides Editors · Editorial team · Updated Sep 2026
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