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Head-to-head · AI Clinical Decision Support Software

OpenEvidence vs ORAYA

  • Updated Nov 2026
  • Both researched from official sources
  • 6 checks side by side
Higher score OpenEvidence #4 in AI Clinical Decision Support Software 8.6/10 Free plan Free plan✓ 0 of 6 features Visit OpenEvidence
ORAYA #6 in AI Clinical Decision Support Software 7.9/10 Pricing on request ✓ 5 of 6 features Visit ORAYA

OpenEvidence leads on 0 checks, ORAYA on 0, and 6 are even. Who comes out ahead on the 6 yes/no, price and count checks where we have data for both products. The editor score weighs everything else too.

Our verdict

  • Highest scoreOpenEvidence · 8.6/10
  • Free planonly OpenEvidence
  • Most featuresORAYA · 5 of 6

OpenEvidence scores higher on our rubric for ai clinical decision support software: 8.6 against 7.9 out of 10; our editors rank them #4 and #6.

OpenEvidence is the better fit for clinicians seeking free, cited mobile clinical answers. ORAYA is the better fit for teams needing chart-aware clinical answers and treatment.

  • OpenEvidence fits best

    Clinicians seeking free, cited mobile clinical answers

  • ORAYA fits best

    Teams needing chart-aware clinical answers and treatment

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Side by side

Feature OpenEvidence 8.6/10 Visit ↗ ORAYA 7.9/10 Visit ↗
At a glance
Editor score 8.6 7.9
Ranking #4 in AI Clinical Decision Support Software #6 in AI Clinical Decision Support Software
Best for Clinicians seeking free, cited mobile clinical answers Teams needing chart-aware clinical answers and treatment
Pricing model Free Paid
Starting price Free Pricing on request
Free plan ✓ (best) Not checked yet
Free trial — —
Deployment Mobile Cloud, Mobile
Platforms iOS, Android Web, iOS, Android
Compliance SOC 2, HIPAA HIPAA
Built for Solo, Small business, Mid-market, Enterprise Small business, Mid-market, Enterprise
Features OpenEvidence 0/6 · ORAYA 5/6
Differential diagnosis Not checked yet ✓ (best)
Treatment recommendations Not checked yet ✓ (best)
Drug interaction support Not checked yet ✓ (best)
Clinical risk prediction Not checked yet Not checked yet
Evidence citations Not checked yet ✓ (best)
EHR integration Not checked yet ✓ (best)
Our review
Pros
  • Answers cite claims to peer-reviewed and other medical sources.
  • EvidenceGrade indicators show the strength of supporting evidence.
  • Mobile apps include Voice Mode, CME and MOC features.
  • Uses chart context for clinical questions and treatment options
  • Checks drug interactions and contraindications
  • Drafts structured visit notes for clinician review and signature
Cons
  • Access is limited to verified healthcare professionals.
  • Mobile deployment may not fit teams seeking desktop access.
  • No verified EHR integrations are described.
  • Pricing and subscription terms are set by clinic agreement
  • Documentation drafts require clinician review and signature
  • HIPAA and SOC 2 compliance are pending
Our verdict

OpenEvidence is a clinical decision-support and medical search platform for verified healthcare professionals. It answers clinical questions using peer-reviewed medical literature, medical journals, FDA and CDC sources, and licensed…

Read the review →

ORAYA is a clinical AI platform for clinicians, pharmacy and PBM teams, and clinical researchers. It answers questions about dosing, safety, and treatment using medical literature and FDA sources, with linked citations and evidence…

Read the review →
  1. OpenEvidenceAI Clinical Decision Support Software 8.6Free plan
  2. ORAYAAI Clinical Decision Support Software 7.9Pricing on request

Strengths and trade-offs

  • OpenEvidence — where it wins

    • Answers cite claims to peer-reviewed and other medical sources.
    • EvidenceGrade indicators show the strength of supporting evidence.
    • Mobile apps include Voice Mode, CME and MOC features.

    Where it doesn't

    • Access is limited to verified healthcare professionals.
    • Mobile deployment may not fit teams seeking desktop access.
    • No verified EHR integrations are described.
  • ORAYA — where it wins

    • Uses chart context for clinical questions and treatment options
    • Checks drug interactions and contraindications
    • Drafts structured visit notes for clinician review and signature

    Where it doesn't

    • Pricing and subscription terms are set by clinic agreement
    • Documentation drafts require clinician review and signature
    • HIPAA and SOC 2 compliance are pending

More comparisons

Reviewed by iTechGuides Editors · Editorial team · Updated Nov 2026

Last updated · How we research and update