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Head-to-head · Cloud Disaster Recovery Software

Datto SIRIS vs Nutanix Prism Central

  • Updated Oct 2026
  • Both researched from official sources
  • 3 checks side by side
Higher score Datto SIRIS #4 in Cloud Disaster Recovery Software 8.6/10 Pricing on request ✓ 2 of 3 features Visit Datto SIRIS
Nutanix Prism Central #8 in Cloud Disaster Recovery Software 8.1/10 Pricing on request ✓ 0 of 3 features Visit Nutanix

Datto SIRIS leads on 0 checks, Nutanix Prism Central on 0, and 3 are even. Who comes out ahead on the 3 yes/no, price and count checks where we have data for both products. The editor score weighs everything else too.

Our verdict

  • Highest scoreDatto SIRIS · 8.6/10
  • Most featuresDatto SIRIS · 2 of 3

Datto SIRIS scores higher on our rubric for cloud disaster recovery software: 8.6 against 8.1 out of 10; our editors rank them #4 and #8.

Datto SIRIS is the better fit for IT teams needing fast recovery for servers and VMs. Nutanix Prism Central is the better fit for nutanix-centered infrastructure recovery.

  • Datto SIRIS fits best

    IT teams needing fast recovery for servers and VMs

  • Nutanix Prism Central fits best

    Nutanix-centered infrastructure recovery

Advertiser disclosure: iTechGuides is reader-supported. Vendors can pay for top positions in our rankings and for a place on other products' pages, and we may earn a commission when you click some links. Bought places stand at the number bought; this page and our disclosure say so. Paying vendors may get a fuller, more detailed review from our editors, and that review can change their score. How we rank.

Side by side

Feature Datto SIRIS 8.6/10 Visit ↗ Nutanix Prism Central 8.1/10 Visit ↗
At a glance
Editor score 8.6 8.1
Ranking #4 in Cloud Disaster Recovery Software #8 in Cloud Disaster Recovery Software
Best for IT teams needing fast recovery for servers and VMs Nutanix-centered infrastructure recovery
Pricing model Paid Paid
Starting price Pricing on request Pricing on request
Free plan Not checked yet —
Free trial — —
Deployment Cloud, Self-hosted Cloud, Self-hosted
Platforms Web Web
Built for Small business, Mid-market, Enterprise Mid-market, Enterprise
Features Datto SIRIS 2/3 · Nutanix Prism Central 0/3
Failover orchestration ✓ (best) Not checked yet
Dependency mapping Not checked yet Not checked yet
Immutable recovery points ✓ (best) Not checked yet
Specs
Replication mode Snapshot Not checked yet
Minimum RPO 5 min Not checked yet
Minimum RTO Not checked yet Not checked yet
Supported workloads physical servers; virtual machines; VMware ESXi; Microsoft Hyper-V Not checked yet
Our review
Pros
  • Incremental backups as often as every five minutes
  • Local and cloud instant virtualization with one-click cloud DR
  • Immutable architecture, ransomware protection, and recovery verification
  • Centralizes management across multiple Nutanix clusters
  • Automates protection plans, backups, and recovery workflows
  • Supports live migration, APIs, and multiple hypervisors
Cons
  • Pricing requires a contact-sales process
  • Deployment spans appliances or virtual appliances plus cloud storage
  • Focused on physical servers and virtual machines rather than broader workloads
  • Broader infrastructure management than dedicated disaster recovery
  • Pricing requires contact with sales
  • Primarily designed for Nutanix infrastructure teams
Our verdict

Datto SIRIS is a hybrid-cloud business continuity and disaster recovery solution from Kaseya for managed service providers and IT departments. It protects physical servers and virtual machines, including VMware ESXi and Microsoft Hyper-V…

Read the review →

Nutanix Prism Central is a multi-cluster management plane for Nutanix Cloud Infrastructure. It is designed for IT infrastructure teams managing virtualized datacenter, edge, and hybrid-cloud environments. From a centralized console, teams…

Read the review →
  1. Datto SIRISCloud Disaster Recovery Software 8.6Pricing on request
  2. Nutanix Prism CentralCloud Disaster Recovery Software 8.1Pricing on request

Strengths and trade-offs

  • Datto SIRIS — where it wins

    • Incremental backups as often as every five minutes
    • Local and cloud instant virtualization with one-click cloud DR
    • Immutable architecture, ransomware protection, and recovery verification

    Where it doesn't

    • Pricing requires a contact-sales process
    • Deployment spans appliances or virtual appliances plus cloud storage
    • Focused on physical servers and virtual machines rather than broader workloads

  • Nutanix Prism Central — where it wins

    • Centralizes management across multiple Nutanix clusters
    • Automates protection plans, backups, and recovery workflows
    • Supports live migration, APIs, and multiple hypervisors

    Where it doesn't

    • Broader infrastructure management than dedicated disaster recovery
    • Pricing requires contact with sales
    • Primarily designed for Nutanix infrastructure teams
  • Datto SIRIS8.6/10 · Pricing on request

    A recovery-focused platform for five-minute backups, virtualization, and cloud disaster recovery.

    Visit Datto SIRISFull verdict →
  • Nutanix Prism Central8.1/10 · Pricing on request

    A broad Nutanix infrastructure management plane with strong recovery workflows.

    Visit NutanixFull verdict →

More comparisons

All cloud disaster recovery software comparisons → · Full ranking →

Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026

Last updated · How we research and update