BIOVIA COSMOtherm (COSMO-RS) vs ProMax

BIOVIA COSMOtherm (COSMO-RS)7.9Visit PProMax7.9Visit

BIOVIA COSMOtherm (COSMO-RS) #2 in Chemical Software 7.9/10 Pricing on request ✓ 0 of 5 features Visit BIOVIA

vs

P ProMax #6 in Chemical Software 7.9/10 Pricing on request ✓ 0 of 5 features Visit ProMax

• BIOVIA COSMOtherm (COSMO-RS) fits best

  Researchers predicting mixture thermodynamics

• ProMax fits best

  Gas-processing and acid-gas simulation teams

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Side by side

Feature	BIOVIA COSMOtherm (COSMO-RS) 7.9/10 Visit ↗	PProMax 7.9/10 Visit ↗
At a glance
Editor score	7.9	7.9
Ranking	#2 in Chemical Software	#6 in Chemical Software
Best for	Researchers predicting mixture thermodynamics	Gas-processing and acid-gas simulation teams
Pricing model	Paid	Paid
Starting price	Not published	Not published
Free plan	—	Not published
Free trial	—	—
Deployment	Desktop	Desktop
Platforms	Windows	Windows
Support	Community, Docs	Email, Phone, Docs
Built for	Mid-market, Enterprise	Mid-market, Enterprise
Features BIOVIA COSMOtherm (COSMO-RS) 0/5 · ProMax 0/5
SDS management	—	Not published
Chemical inventory	—	Not published
Formulation management	—	Not published
Regulatory compliance	—	Not published
Mobile access	—	Not published
Specs
Deployment	On-premises	Not published
Our review
Pros	Predicts solubility across liquids, solids and gases Covers phase equilibria, partitioning, vapor pressure and pKa Offers graphical workflows and command-line batch processing	Models acid-gas removal with amine solvents and reaction kinetics. Connects models to PI, OPC-HDA, ODBC databases, and Excel. Combines optimization with pipeline, corrosion, and emissions tools.
Cons	Windows desktop deployment limits platform flexibility Contact-sales pricing makes cost assessment less direct Specialized thermodynamics scope is narrower than process simulation	Runs as a Windows desktop product, limiting platform options. Uses contact-sales pricing rather than published plan tiers. Its focus is process simulation, not chemical inventory or SDS management.
Our verdict	BIOVIA COSMOtherm applies COSMO-RS to predict thermodynamic properties of molecules in pure and mixed liquids. Its intended audience includes researchers and teams in chemistry, chemical engineering, formulation, drug development,… Read the review →	ProMax is process simulation software from Bryan Research & Engineering for engineers in oil and gas, refining, treating, and related process industries. It is particularly suited to gas-processing teams working on acid-gas removal and… Read the review →

Strengths and trade-offs

• BIOVIA COSMOtherm (COSMO-RS) — where it wins

  • Predicts solubility across liquids, solids and gases
  • Covers phase equilibria, partitioning, vapor pressure and pKa
  • Offers graphical workflows and command-line batch processing

  Where it doesn't

  • Windows desktop deployment limits platform flexibility
  • Contact-sales pricing makes cost assessment less direct
  • Specialized thermodynamics scope is narrower than process simulation

• ProMax — where it wins

  • Models acid-gas removal with amine solvents and reaction kinetics.
  • Connects models to PI, OPC-HDA, ODBC databases, and Excel.
  • Combines optimization with pipeline, corrosion, and emissions tools.

  Where it doesn't

  • Runs as a Windows desktop product, limiting platform options.
  • Uses contact-sales pricing rather than published plan tiers.
  • Its focus is process simulation, not chemical inventory or SDS management.

• BIOVIA COSMOtherm (COSMO-RS)7.9/10 · Pricing on request

  A specialized COSMO-RS tool for predicting molecular properties in pure and mixed liquids.

  Visit BIOVIAFull verdict →
• PProMax7.9/10 · Pricing on request

  A focused Windows simulator for gas treating, plant models, and process optimization.

  Visit ProMaxFull verdict →