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Choose Amazon Bedrock when AWS-operated inference, AWS governance integration, or applicable AWS compliance coverage is central to your design. Choose Anthropic’s direct API when you want Anthropic’s first-party API and platform capabilities. There is also a third route: Claude Platform on AWS, accessed through an AWS account but operated by Anthropic. These are different services, not interchangeable ways to reach the same endpoint.

How the three options differ

The key architectural question is who operates inference and which API surface your application will use. AWS distinguishes Bedrock from Claude Platform on AWS by operator, data processing, API access, and compliance coverage. The direct Anthropic API is also operated by Anthropic. See AWS’s service comparison and Claude Platform on AWS overview.

Route Inference operator What it is suited to
Amazon Bedrock AWS AWS-operated Claude inference and Bedrock’s AWS-integrated service and API options.
Anthropic API Anthropic Direct access to Anthropic’s first-party API and platform.
Claude Platform on AWS Anthropic; AWS provides account access and billing integration Anthropic-operated Claude platform access through an AWS account. AWS documents same-day availability with the first-party Claude API, plus Agent Skills, code execution, and extended thinking.

The platform details in the final row are described by AWS’s Claude Platform on AWS documentation. Do not assume that a feature available through Anthropic’s platform is automatically available through Bedrock: Bedrock support depends on the model and integration.

Choose based on your architecture and requirements

  • Favor Bedrock if AWS should operate the inference service, your application already depends on AWS identity, governance, or model-provider integration, or your workload requires AWS compliance coverage. Confirm the exact contractual terms and compliance scope for your account and use case.
  • Favor Anthropic’s direct API if your priority is Anthropic’s first-party API and platform capabilities.
  • Evaluate Claude Platform on AWS if you want Anthropic-operated inference accessed through an AWS account, or need a platform feature AWS specifically documents there. Confirm feature availability and access terms for your account.
  • Check the model and endpoint before choosing if your decision depends on a specific Claude model, API family, or AWS Region. Compatibility and availability are not uniform.

These are product and architecture distinctions, not evidence that one route is universally faster, cheaper, or more reliable.

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Compare the API and integration surface

Bedrock offers several API families: Invoke for synchronous, streaming, bidirectional streaming, and asynchronous invocation; Converse for a unified multi-turn interface; Anthropic-compatible Messages requests; and OpenAI-compatible Chat Completions and Responses interfaces. A model does not necessarily support every family. AWS’s API compatibility table lists the supported interfaces model by model; check it for your selected model rather than assuming an API is available across Claude models.

AWS’s Claude documentation also notes that supported modalities, features, and Regions vary by model. Use its Claude model guidance alongside the compatibility table when selecting an integration.

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Choose the Bedrock endpoint deliberately

AWS says, “For most new applications, use the bedrock-runtime endpoint.” It identifies bedrock-mantle for capabilities currently available only there, including server-side and pre-configured tools, background inference, Projects, or Workspaces. Check the Bedrock endpoint guidance against the capability your application needs.

Check data processing, compliance, and routing

AWS identifies AWS as the data processor for Bedrock, and both Anthropic and AWS as data processors for Claude Platform on AWS. AWS describes Claude Platform on AWS as a third-party offering that is not covered by standard AWS compliance programs, certifications, or audit reports, including SOC, ISO, and HIPAA eligibility. If a workload requires a particular AWS compliance program, Bedrock is the AWS-operated Claude option to evaluate—but verify the required certification, service scope, account terms, and geography rather than treating coverage as universal. These distinctions are set out in AWS’s comparison.

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Bedrock routing also affects where inference can run. AWS documents direct in-Region inference, geographic cross-Region inference, and global cross-Region inference profiles. Direct inference stays in the specified Region; geographic routing can use Regions within the selected geography; global routing can use supported commercial Regions worldwide. If residency constraints matter, confirm the selected model and profile in AWS’s regional availability documentation.

Retention terms need account-level verification. AWS’s migration documentation says AWS is the data processor on Bedrock and Anthropic does not retain inference inputs or outputs there; on Claude Platform on AWS, Anthropic is the data processor and Zero Data Retention is available on request through an Anthropic account representative. Confirm current enrollment and contract terms before relying on a retention configuration. See AWS’s migration guidance.

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Budget with your workload, not a blanket price claim

There is no established like-for-like cost result for a defined workload that supports a general claim that Bedrock or the direct API is cheaper. Pricing depends on model, Region or endpoint, input and output mix, service tier, caching, and traffic pattern. AWS says rate limits and quotas are managed by AWS for Bedrock and by Anthropic for Claude Platform on AWS. Check the current price sheets and the quota limits for the account and route you plan to use; the AWS comparison describes the quota-management distinction.

The same caution applies to latency, availability, and output quality: do not infer a winner from feature descriptions. For a production decision, benchmark the same model and version, prompts, Region, streaming behavior, concurrency, retry policy, and application network path in the target accounts.

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Plan a migration as an integration change

Moving from Bedrock to Claude Platform on AWS is not just changing a URL. AWS lists changes to the base URL, API format, model IDs, SDK client and package, streaming format, request headers, and Region availability. SigV4 signing remains supported, but the signing context changes. Inventory these dependencies and verify target-region and model support before switching traffic. See AWS’s migration guide.