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Open Windows Security, select Virus & threat protection, then choose Manage settings. For most personal PCs, keep Real-time protection and Tamper protection on, review cloud and sample-submission settings, and install current protection updates. Check which antivirus provider is active before changing Defender settings, especially if you use another antivirus product.

Open Virus & threat protection

  1. Open Start, search for Windows Security, and launch the app.
  2. Select Virus & threat protection. To reach the same app through Windows 11 Settings, go to Settings > Privacy & security > Windows Security.
  3. Select Manage settings under Virus & threat protection to view Defender’s main protection controls.

Windows Security is the interface; Microsoft Defender Antivirus is the built-in antivirus component in Windows 10 and Windows 11. Labels and availability can vary by Windows version and configuration. On a work- or school-managed device, some settings may be unavailable or controlled by your organization; ask your IT administrator if a control is missing. See Microsoft’s Virus & threat protection guide and its antivirus FAQ.

Check protection status and scan the PC

On the Virus & threat protection page, review Current threats and the last-scan information. A Quick scan checks common locations; choose the other scan options when you need a fuller or custom check.

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To check a particular file or folder, right-click it in File Explorer and choose Scan with Microsoft Defender. In Windows 11, this command may be inside Show more options. Microsoft’s instructions are in Scan an item with Windows Security.

Choose settings in Manage settings

Real-time protection: leave it on

Real-time protection monitors files and programs as they are accessed or run. Keep it enabled for ordinary use. While it is off, opened and downloaded files are not scanned in real time; a file downloaded or installed during that period may not be checked until a later scheduled scan. Microsoft says the control turns itself back on after a short while, and scheduled scans continue. Avoid treating a temporary pause as a safe way to install or open a questionable file.

Cloud-delivered protection and automatic sample submission

Microsoft recommends enabling both settings for optimal protection. Cloud-delivered protection allows Defender to receive updated protection improvements when the device is online. With automatic sample submission enabled, suspicious files may be sent to Microsoft for evaluation. Microsoft says it will alert you if a requested file may contain personal information so you can decide whether to send it.

Rank #2
Dell Latitude 5420 14" FHD Business Laptop Computer, Intel Quad-Core i5-1145G7, 16GB DDR4 RAM, 256GB SSD, Camera, HDMI, Windows 11 Pro (Renewed)
  • 256 GB SSD of storage.
  • Multitasking is easy with 16GB of RAM
  • Equipped with a blazing fast Core i5 2.00 GHz processor.

Tamper protection

Keep Tamper protection on where it is available. It helps prevent malicious apps from changing important Defender settings, including real-time and cloud-delivered protection. Administrators can still change settings in Windows Security; other apps cannot change them while tamper protection is on.

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Protection updates

Check the Protection updates area and select Check for updates if needed. Windows Update automatically downloads security intelligence—also called definitions—which Defender uses during scans. Microsoft explains these controls in Virus and Threat Protection in the Windows Security App.

Rank #3

Use Controlled folder access for added ransomware protection

Controlled folder access can limit unauthorized changes to files in protected folders. Open Virus & threat protection > Manage ransomware protection and consider turning on Controlled folder access. When enabled, common folders such as Documents, Pictures, Videos, Music, and Desktop are protected by default; you can add other folders.

If a trusted app is blocked, allow it only if it genuinely needs access to protected files. An allowed app can access those files, so a compromised allowed app could put them at risk. Microsoft’s guidance is available in Protect your PC from ransomware.

Rank #4
15.6 Inch Laptop Computer, N4020, 4GB DDR4 RAM, 128GB eMMC,with Windows 11
  • EFFORTLESS EVERYDAY PERFORMANCE: Powered by Intel Celeron N4020 processor and Windows 11 Home system, delivering reliable, low-power efficiency for daily tasks like document editing, email, online classes, and web browsing
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Add exclusions only for a specific reason

An exclusion tells Defender not to check a selected file, folder, file type, or process during real-time scanning. That reduces protection for the excluded item and can leave the device or its data vulnerable. Microsoft notes that scheduled scans or a third-party antimalware product might still scan an excluded item; do not assume that means the exclusion is harmless.

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  • Exclude only an item you recognize and have a specific reason to exempt.
  • For a process exclusion, Microsoft recommends entering the full path and filename.
  • Remove the exclusion when it is no longer needed.

Microsoft describes exclusion behavior and its risks in its Windows Security settings guide.

Best Value
Windows 11 Laptop with i3 Processor 15.6" Work Laptop for College Students
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Check which antivirus provider is active

If you install another antivirus or antimalware product, Defender Antivirus goes into disabled mode automatically while that product is running. After the other product is uninstalled, Defender should return to active mode automatically. Confirm the status instead of assuming which product is protecting the PC: open Windows Security > Virus & threat protection and select Manage providers.

Disabling Defender without another active security product leaves the device vulnerable. Microsoft’s antivirus FAQ explains the built-in antivirus behavior, and its Windows Security scanning guide covers the app’s controls. These sources explain how provider switching works, not how to rank antivirus vendors.

Protect important files with recovery options

Antivirus settings reduce risk, but they are not a substitute for a way to recover files. Microsoft recommends keeping Windows current, enabling Controlled folder access, and storing important files on OneDrive. Microsoft says OneDrive includes ransomware detection and recovery as well as file versioning; Microsoft 365 advanced protection offers ransomware detection and recovery. These benefits depend on the service and plan, so check current eligibility and availability for your region in Microsoft’s ransomware protection guidance and Windows Security overview.

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Quick Recap

Bestseller No. 1
Bestseller No. 2
Dell Latitude 5420 14' FHD Business Laptop Computer, Intel Quad-Core i5-1145G7, 16GB DDR4 RAM, 256GB SSD, Camera, HDMI, Windows 11 Pro (Renewed)
Dell Latitude 5420 14" FHD Business Laptop Computer, Intel Quad-Core i5-1145G7, 16GB DDR4 RAM, 256GB SSD, Camera, HDMI, Windows 11 Pro (Renewed)
256 GB SSD of storage.; Multitasking is easy with 16GB of RAM; Equipped with a blazing fast Core i5 2.00 GHz processor.
$285.00
Bestseller No. 3
HP 14' HD Laptop, Windows 11, Intel Celeron Dual-Core Processor Up to 2.60GHz, 4GB RAM, 64GB SSD, Webcam, Dale Pink (Renewed)
HP 14" HD Laptop, Windows 11, Intel Celeron Dual-Core Processor Up to 2.60GHz, 4GB RAM, 64GB SSD, Webcam, Dale Pink (Renewed)
14" diagonal, 1366x768 resolution, HD BrightView LED, Glossy NON-TOUCH Display
$245.99

Product prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on Amazon at the time of purchase will apply.