The Tool Desk
Outbyte Driver Updater FREEScan for outdated or missing drivers - takes under a minuteDriver Scan →Outbyte PC Repair FREERepair Windows errors before they cause bigger problemsFix Now →A full, six-sided zippered mattress encasement can help contain bed bugs inside a mattress and can block certain allergens when its materials and closure are designed for that purpose. It is not a stand-alone bed-bug treatment or a guarantee of allergy relief. The title’s phrase “Best Block” is not substantiated as a specific product or brand in the sources reviewed; CleanRest, Protect-A-Bed AllerZip, and Mattress Safe are distinct examples, not interchangeable products or a verified “best” ranking.
What a mattress encasement can—and cannot—do
An encasement surrounds all sides of a mattress and closes with a zipper. EPA label guidance recommends using one on mattresses and other large items that cannot be washed to keep bed bugs contained and prevent bites. The label describes this as one component of a broader control process, not a promise that encasing a mattress will eradicate an infestation elsewhere in a room or home. EPA label guidance
For allergens, protection depends on the particular product’s fabric and closure, and on the specific allergen claim the manufacturer makes. A barrier claim does not establish that a product will relieve symptoms or provide a clinical benefit for every user.
What to compare before buying
- Coverage: Confirm that the product encloses all six mattress sides rather than covering only the top.
- Zipper security: Look for a fully enclosed zipper and a described closure feature intended to prevent gaps. Names such as Zip-N-Click and BugLock are manufacturer-described systems, not independent proof of performance.
- Specific claims and evidence: Separate bed-bug claims from allergen claims. Check whether a stated result comes from the manufacturer or an independent test, and whether it applies to the exact product and sample.
- Fit: Match the encasement’s depth range to the mattress, including any pillow-top or added topper that will remain inside it. Check current dimensions for the exact model.
- Waterproofing and care: Verify whether waterproofing is stated for the whole encasement and read the care instructions. Washing temperature and methods can be model-specific.
- Warranty and price: Review current terms directly with the seller or manufacturer. The sources cited here do not establish a comparable price or warranty across these products.
Examples of product claims—and how to read them
These examples illustrate differences in manufacturer descriptions; they are not a head-to-head ranking or proof that one product is best for every mattress.
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#1 Best Overall
- 360° Coverage Protection - Fits 54 inches by 75 inches full size mattress up to 13 inches deep, fully encasing all sides. The stretchy fabric slips on easily and stays securely in place without shifting. Refer to the installation video below for step-by-step guidance.
- Soft and Durable Fabric - The non-crinkling design keeps the full size mattress cover quiet and comfortable without feeling stiff. Made from smooth, knitted polyester, that lays flat across the mattress.
- Secure Zippered Closure - The wrap-around zipper encloses the mattress for a tight, secure fit. The mattress protector is designed to provide all-around coverage without shifting.
- 100% Waterproof Liquid Barrier - A protective waterproof layer helps block spills, sweat, drinks and everyday accidents from reaching the mattress, ideal for homes with kids or pets.
- Easy Machine Care – The full size mattress encasement is simple to maintain. Machine wash and tumble dry on low heat with your regular laundry to keep it clean. Note: Packaging may vary slightly.
| Product or source | What the cited source says | How to interpret it |
|---|---|---|
| CleanRest PRO / CleanBrands | CleanBrands describes a waterproof encasement with MicronOne fabric and a Zip-N-Click closure. CleanRest product information and CleanBrands information | These are manufacturer descriptions. Confirm the model’s current specifications and fit before purchase. |
| Protect-A-Bed AllerZip | The manufacturer describes six-sided waterproofing, a BugLock closure, and protection against dust mites and allergens. It lists mattress-depth ranges of 6–11 inches and 11–18 inches, and machine washing in hot water at 130°F. Protect-A-Bed AllerZip | These are product-specific manufacturer statements; check the current listing and label for your exact size and care instructions. |
| Mattress Safe testing information | The company’s testing page cites a 1999 paper on bedding-encasement pore size and allergen blocking. It says results apply only to the specific submitted sample or samples. Mattress Safe testing information | A test result for a submitted sample should not be generalized to every product, model, or later production run. |
How to interpret published bed-bug test figures
CleanBrands reports figures from a study it describes on its own site; the reviewed page does not provide complete study details or a publication date. Treat the numbers as company-reported results for that described study—not as a general property of mattress encasements:
- CleanBrands says zero bugs pierced its fabric or escaped through its Zip-N-Click closure in the described study.
- It reports that an average of 53% of bugs escaped when the study’s control container was used.
- It reports a comparison of 150.5 lb of pressure for its fabric versus 19.0 lb for a competitor’s product.
The company also states that “zero bugs were able to pierce through the fabric and bite the human forearm used in the study” and that “zero bed bugs were able to escape.” The claims and figures are attributable to CleanBrands; the page information cited here does not establish a universal result or provide enough detail to independently assess the study design.
Rank #2
- Bed Bug Mattress Encasement Sealed on All Six Sides: The nylon zipper closure glides around three sides and tucks under a stitched guard flap, leaving no open corner or gap at the pull; sleep tight knowing nothing crawls in and nothing crawls out
- Jersey Knit Mattress Encasement, Soft and Quiet: The knitted polyester face feels more like a soft T-shirt than plastic, silky smooth and silent as you turn over; the breathable jersey fabric handles a warm wash and low tumble dry and keeps its shape
- Waterproof Mattress Cover for Spills and Night Accidents: A waterproof layer sealed beneath the knit helps keep sweat, spills, and wet nights off your mattress; ideal for kids still learning, and when a mess happens it unzips and washes like a sheet
- Dust Mite Mattress Cover and Allergen Barrier: The tight knit and sealed zipper keep dust mite allergens shut inside the mattress instead of drifting into bedding; and rest easier knowing the fabric on your skin is OEKO-TEX Standard 100 certified
- Size and Depth: This Queen mattress encasement fits a mattress measuring 60 by 80 inches and 12 inches deep, stretching up to 13; measure yours first, then slip this zippered waterproof bed bug proof cover down like a pillowcase, and zip it closed
Mattress Safe’s testing page likewise cautions that findings apply only to the specific submitted sample or samples. It references Vaughn JW, McLaughlin TE, Perzonowski MS, and Platts-Mills TAE, “Evaluation of materials used for bedding encasement: effect of pore size in blocking cat and dust mite allergen,” Journal of Allergy and Clinical Immunology 103 (1999): 227–231. The cited page does not provide a numerical result that can responsibly be used as a universal performance claim. Mattress Safe testing information
Using an encasement as part of bed-bug control
EPA label guidance describes encasements as a way to keep bed bugs in a mattress contained and from biting, while also advising multiple treatment steps over time. If a severe infestation persists after one month, the label advises contacting a professional pest-management company. Follow the label and product instructions for any pesticide use; an encasement is not a substitute for treating other affected areas. EPA label guidance
Rank #3
- 100% Waterproof - Six-sided premium mattress protector blocks perspiration, bed wetting, liquids and stains; 10-year quality guarantee (NOTE: For frequent accidents and easy clean-ups, place a fitted SureGuard Mattress Protector over the encasement).
- Bed Bug Proof - Super fine zipper with Invisi-Zip and SureSeal technology completely seals off the mattress from bed bugs - use with a SureGuard Box Spring Encasement
- Keeps Your Mattress Clean & Fresh - Blocks dust, dirt and dander on all sides.
- Soft & Noiseless - 100% cotton terry top; Wicks away moisture; Retains the feel of your mattress - Free from Vinyl, PVC, Phthalates, fire retardants and other toxic chemicals
- Queen (60 in x 80 in) - Fits 13 to 16 inches deep; Zippered Mattress Encasement - Machine wash and dry. Independently lab tested and GREENGUARD Gold certified.
Bottom line for shoppers
Choose based on the mattress’s dimensions, complete coverage, closure design, the exact bed-bug or allergen claim you need, and the evidence and care instructions for that specific model. A manufacturer’s test figure may be useful context, but it is not the same as independently documented evidence that applies across products. Sleep Foundation’s 2026 shopping guide also frames encasements around differing allergen, bed-bug, and waterproofing goals; use it as shopping context rather than a replacement for product-specific evidence. Sleep Foundation’s mattress-encasement guide
Quick Recap
Best Value
- 360° Coverage Protection - Fits 72 inches by 84 inches california king size mattress up to 15 inches deep, fully encasing all sides. The stretchy fabric slips on easily and stays securely in place without shifting. Refer to the installation video below for step-by-step guidance.
- Soft and Durable Fabric - The non-crinkling design keeps the california king size mattress cover quiet and comfortable without feeling stiff. Made from smooth, knitted polyester, that lays flat across the mattress.
- Secure Zippered Closure - The wrap-around zipper encloses the mattress for a tight, secure fit. The mattress protector is designed to provide all-around coverage without shifting.
- 100% Waterproof Liquid Barrier - A protective waterproof layer helps block spills, sweat, drinks and everyday accidents from reaching the mattress, ideal for homes with kids or pets.
- Easy Machine Care – The california king size mattress encasement is simple to maintain. Machine wash and tumble dry on low heat with your regular laundry to keep it clean. Note: Packaging may vary slightly.
Rank #4
- 360° Coverage Protection - Fits 39 inches by 75 inches twin size mattress up to 13 inches deep, fully encasing all sides. The stretchy fabric slips on easily and stays securely in place without shifting. Refer to the installation video below for step-by-step guidance.
- Soft and Durable Fabric - The non-crinkling design keeps the twin size mattress cover quiet and comfortable without feeling stiff. Made from smooth, knitted polyester, that lays flat across the mattress.
- Secure Zippered Closure - The wrap-around zipper encloses the mattress for a tight, secure fit. The mattress protector is designed to provide all-around coverage without shifting.
- 100% Waterproof Liquid Barrier - A protective waterproof layer helps block spills, sweat, drinks and everyday accidents from reaching the mattress, ideal for homes with kids or pets.
- Easy Machine Care – The twin size mattress encasement is simple to maintain. Machine wash and tumble dry on low heat with your regular laundry to keep it clean. Note: Packaging may vary slightly.
Product prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on Amazon at the time of purchase will apply.
