The Tool Desk
Outbyte Driver Updater FREEFix the driver behind crashes, sound loss and screen glitchesFind Drivers →Outbyte PC Repair FREEClear out junk files and repair common Windows errorsFree Scan →iTechGuides is reader-supported. When you buy through links on our site, we may earn an affiliate commission. As an Amazon Associate I earn from qualifying purchases. Learn more
Urine tests for lung cancer are being studied, but none is established for routine screening. A 2024 study found that two urine metabolites could help identify nonsmokers at elevated risk who might be candidates for low-dose CT (LDCT); the authors say prospective studies are still needed. The findings do not show that a urine test can diagnose cancer, replace a CT scan, or improve survival.
Can a urine test detect lung cancer early?
Researchers are investigating whether signals in urine can help identify lung cancer or flag people for further evaluation. One line of research measures creatine riboside (CR) and N-acetylneuraminic acid (NANA), two metabolites. Other studies examine different signals, including microRNA carried in extracellular vesicles and biosensor readings. These are distinct approaches, not versions of one interchangeable test.
What the CR and NANA study found
A 2024 study published in Clinical Cancer Research measured urine metabolites with liquid chromatography–mass spectrometry. It compared people with lung cancer with age- and sex-matched controls in an exploratory cohort of 846 participants and an independent validation cohort of 505. The study included analysis of nonsmokers, who do not meet the smoking-history criteria in the cited US screening recommendation.
Recommended Free Tools
For the combined CR and NANA analysis among nonsmokers, the area under the receiver operating characteristic curve (AUC) was 0.94 in the exploratory cohort and 0.80 in the validation cohort. AUC describes how well a model separates cases from controls in the studied data; it is not the chance that a person with a positive result has cancer. These results also do not establish performance in routine population screening or show that testing improves health outcomes. The study authors said the biomarkers could help identify high-risk nonsmokers as candidates for LDCT and that prospective studies are warranted. Read the 2024 study.
#1 Best Overall
- Read Before You Buy — No Video Output: These adapters support charging and USB 2.0 data transfer, but cannot transmit video signals. Except for standard USB webcams (which use USB data only), they are not compatible with HDMI/DisplayPort cables, video-capable USB-C hubs, or docking stations with video output.
- Convert USB-A Ports to USB-C: Designed to connect USB-C earphones, cables, flash drives, card readers, and other USB-C accessories to standard USB-A ports. Plug-and-play with no drivers or software required.
- Aluminum Alloy Housing: Built with a sturdy aluminum alloy shell that aids in heat dissipation and protects against daily wear and scratches. Designed to maintain a stable and secure connection.
- Compact & Travel-Friendly: The ultra-compact design allows the adapter to stay plugged into your device without blocking adjacent ports or adding bulk, reducing wear and tear on your original USB ports.
- 12-Month Warranty: Backed by a 12-month manufacturer warranty for peace of mind. Designed to meet strict quality control standards for reliable everyday performance.
Other urine-based approaches
Earlier work also explored urinary metabolites. A 2014 study reported CR and NANA as candidate diagnostic and prognostic markers; a 2016 prospective cohort study examined whether metabolites were elevated before diagnosis and reported associations between CR and lung cancer risk, with results varying by population subgroup. Neither establishes a recommended screening assay. 2014 study; 2016 cohort study.
Two separate reports published in 2026 describe other technologies. A case-control study of urinary extracellular-vesicle microRNA reported early-stage detection sensitivity and specificity of 82.0% and 92.5% in a training set, and 88.2% and 87.0% in a test set. A separate biosensor report described a 238-patient cohort and reported sensitivity of 91%, specificity of 86%, and AUC of 0.86. These are results from their respective study cohorts, not established population-screening performance, and cannot be compared as if the studies tested the same assay in the same people. MicroRNA study; Biosensor report.
Rank #2
- 5-in-1 USB-C Hub: Experience comprehensive connectivity featuring a Power Delivery input, two USB-A 2.0 ports, a USB-A 3.0 port, and an HDMI port. (Note: The USB-C power delivery input port is only for connecting an external wall charger to power your laptop and cannot power peripheral devices.)
- 90W Pass-Through Charging: Achieve optimal charging with 90W pass-through power to your laptop, supported by a total input of 100W, with the hub reserving 10W for operational efficiency. (Note: Wall charger not included.)
- Quick Data Transfers: Accelerate your productivity with rapid data transfers using a high-speed 5Gbps USB 3.0 port and two 480Mbps USB 2.0 ports.
- 4K HDMI Display: Enhance your visual experience with a hub capable of delivering 4K resolution at 30Hz in both mirror and extend modes. Please note that this hub is compatible with MacBook (macOS 12 and newer), Windows 10 and 11, ChromeOS, and laptops equipped with DP Alt Mode and Power Delivery. Note: This device is not compatible with Linux.
- What You Get: Anker USB-C Hub (5-in-1, 4K HDMI), welcome guide, 18-month warranty, and our friendly customer service.
Is a urine screening test available now?
The studies cited here do not establish a urine test for routine lung cancer screening or a consumer test that readers can use to determine whether they have cancer. The CR and NANA work uses laboratory analysis, and the other approaches remain research-stage in the cited reports. A urine biomarker result should not be treated as a diagnosis.
Can a urine test replace a CT scan?
No. The cited evidence does not show that urine testing can replace LDCT, or that screening with a urine test reduces deaths from lung cancer. In the United States, the US Preventive Services Task Force (USPSTF) recommendation says biomarker measurement has not been found beneficial as a screening modality. It recommends annual LDCT for eligible high-risk adults. Read the USPSTF recommendation.
Rank #3
- Sleek 7-in-1 USB-C Hub: Features an HDMI port, two USB-A 3.0 ports, and a USB-C data port, each providing 5Gbps transfer speeds. It also includes a USB-C PD input port for charging up to 100W and dual SD and TF card slots, all in a compact design.
- Flawless 4K@60Hz Video with HDMI: Delivers exceptional clarity and smoothness with its 4K@60Hz HDMI port, making it ideal for high-definition presentations and entertainment. (Note: Only the HDMI port supports video projection; the USB-C port is for data transfer only.)
- Double Up on Efficiency: The two USB-A 3.0 ports and a USB-C port support a fast 5Gbps data rate, significantly boosting your transfer speeds and improving productivity.
- Fast and Reliable 85W Charging: Offers high-capacity, speedy charging for laptops up to 85W, so you spend less time tethered to an outlet and more time being productive.
- What You Get: Anker USB-C Hub (7-in-1), welcome guide, 18-month warranty, and our friendly customer service.
The CR and NANA study’s proposed role is potential risk triage: identifying people who might warrant LDCT, not substituting a urine result for imaging. Whether the biomarkers can do that safely and usefully in practice remains to be established through prospective studies.
Independent reader supportYour contribution helps us test, update, and keep practical guides available for everyone.Who should get lung cancer screening?
The USPSTF recommendation published March 9, 2021 applies in the United States. It recommends annual LDCT for adults aged 50 to 80 who have at least a 20 pack-year smoking history and currently smoke or quit within the past 15 years. A pack-year means smoking an average of one pack per day for one year; clinicians can help calculate a person’s history.
Rank #4
- Dual Converters, Infinite Potential：Includes 2× USB C male to USB A female adapters and 2× USB A male to USB C female adapters. Perfect for a wide range of uses—tablets with Bluetooth keyboards, expand USB ports on macbook, and more. Two different converters for all your daily needs
- Next-Level 10Gbps & 3A Charging: No more slow 480Mbps, this usb to usb c adapter has a transfer speed of up to 10Gbps, allowing you to do more transferring in less time. This usb adapter fits both USB A and USB C charger, supporting up to 3A fast charging
- Upgraded Exquisite Craftsmanship: With an aluminum alloy housing and metal connector, the usbc to usb adapter is extremely durable and sturdy. Rigorously tested to withstand more than 10,000 times of plugging and unplugging, ensuring long-lasting performance
- Broad Compatible: The usb c to usb adapter widely supports all USB C/ USB A devices like laptops, tablets, cellphones, car chargers, and phone chargers. Such as compatible with MacBook Pro/Air 2023/2022, Thunderbolt 4/3 Devices,Apple MagSafe Watch 9/8/7/SE/Ultra, iPad Pro 2022/2021, Samsung Galaxy S23/S20/S10, and iPhone 17/16/15 Pro. Plug and play
- Please Note: To reach 10Gbps speed, keep the cable under 3.3 ft. For USB A Male to USB C adapters, try flipping the USB C connector. USB C Male to USB A adapters support bidirectional 10Gbps transfer within 3.3 ft
- Screening should stop once a person has not smoked for 15 years.
- It should also stop if a health problem substantially limits life expectancy or the ability or willingness to undergo curative lung surgery.
Guidelines can change, and eligibility depends on individual circumstances. If you may qualify, discuss LDCT with a clinician rather than waiting for or seeking an unvalidated urine test. People outside these criteria can ask a clinician about their individual risk; the cited recommendation does not establish urine biomarkers as an alternative screening route.
Quick wins for a faster PC:
Clear out junk files and repair common Windows errorsFree Scan →Fix the driver behind crashes, sound loss and screen glitchesFind Drivers →Quick Recap
Best Value
- 5-in-1 Connectivity: Equipped with a 4K HDMI port, a 5 Gbps USB-C data port, two 5 Gbps USB-A ports, and a USB C 100W PD-IN port. Note: The USB C 100W PD-IN port supports only charging and does not support data transfer devices such as headphones or speakers.
- Powerful Pass-Through Charging: Supports up to 85W pass-through charging so you can power up your laptop while you use the hub. Note: Pass-through charging requires a charger (not included). Note: To achieve full power for iPad, we recommend using a 45W wall charger.
- Transfer Files in Seconds: Move files to and from your laptop at speeds of up to 5 Gbps via the USB-C and USB-A data ports. Note: The USB C 5Gbps Data port does not support video output.
- HD Display: Connect to the HDMI port to stream or mirror content to an external monitor in resolutions of up to 4K@30Hz. Note: The USB-C ports do not support video output.
- What You Get: Anker 332 USB-C Hub (5-in-1), welcome guide, our worry-free 18-month warranty, and friendly customer service.
Product prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on Amazon at the time of purchase will apply.
