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In an updated Cochrane review summarized by ScienceDaily on October 8, 2026, nicotine e-cigarettes helped more people quit smoking than nicotine replacement therapy (NRT), such as gum or patches. The reported difference was about four additional quitters per 100 people. That is a quit-rate comparison—not evidence that vaping is harmless or the right option for everyone.

What did the review find?

The living systematic review included 80 randomized controlled trials and 29,861 participants. Nine trials were newly added in the 2026 update, according to the ScienceDaily summary, which attributes the findings to Cochrane.

The reported advantage depends on what nicotine e-cigarettes were compared with. The summary describes the comparison with NRT as high-certainty evidence; it says the comparison with behavioral support or no support is less certain because of possible bias in some study designs.

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Comparison Reported result Certainty or qualification in the summary
Nicotine e-cigarettes versus NRT, including gum and patches About 4 additional people quit per 100 with nicotine e-cigarettes High-certainty evidence, as characterized by the summary
Nicotine e-cigarettes versus non-nicotine e-cigarettes About 2 additional people quit per 100 with nicotine e-cigarettes The summary does not state a certainty rating for this comparison
E-cigarettes versus behavioral support or no support The summary reports higher quit rates among people given e-cigarettes Lower confidence because of possible bias in some study designs; no absolute difference is stated

The figures are absolute differences per 100 people, not percentage-point changes stated against a specific baseline quit rate. The ScienceDaily summary does not provide the underlying quit rates, confidence intervals, or exact outcome definitions, so those details cannot be inferred from the reported differences.

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How should you interpret “four more quitters per 100”?

It means that, in the review’s comparison, about four more people out of every 100 quit with nicotine e-cigarettes than with NRT. It does not mean that four out of every 100 people who vape will quit, or that a particular person is four times as likely to succeed. Individual outcomes can differ, and the summary does not give enough detail to calculate an individual’s chance of quitting.

The result supports nicotine e-cigarettes as an effective option for smoking cessation compared with NRT in the reviewed trials. It does not establish that e-cigarettes are the best choice for every smoker, or that NRT and other support are ineffective.

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Does the finding mean vaping is safe?

No. The summary says researchers found no evidence that using e-cigarettes to quit increased serious harm, but it also says longer-term research is needed. “No evidence of increased serious harm” is not the same as proof of no risk.

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The safety statement applies to regulated, nicotine-containing e-cigarettes discussed in the summary. It should not be extended to unlicensed products or products containing other substances, including THC, which can have different risks. Nor does a comparison of quit rates establish that vaping is harmless.

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How do you choose a quit-smoking approach?

There is no single method that the summary identifies as right for everyone. Consider the evidence alongside your circumstances and discuss suitable options with a clinician or stop-smoking support service, as the summary recommends.

  • If considering an e-cigarette, the reported findings concern regulated products containing nicotine used to quit smoking—not unlicensed devices or products with other substances.
  • If considering NRT, the review’s comparison included options such as gum and patches; the summary does not identify a particular product or dose as superior.
  • Ask a clinician or stop-smoking service to help match an approach to your needs and to discuss support alongside the chosen quit aid.
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What the evidence does not establish

The October 8, 2026 ScienceDaily report identifies the review as “Electronic cigarettes for smoking cessation,” published in the Cochrane Database of Systematic Reviews in 2026. The report does not supply subgroup results, confidence intervals, or detailed methods, so its headline comparison should be read at the level it reports: a modest average advantage in quitting over NRT, not a guarantee for any individual.

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