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Head-to-head · Guitar Amp Software

GENOME vs TH-U

  • Updated Oct 2026
  • Both researched from official sources
  • 6 checks side by side
Higher score GENOME #3 in Guitar Amp Software 9.1/10 Free plan · 14-day trial Free planFree trial✓ 2 of 2 features Visit Two notes
TH-U #5 in Guitar Amp Software 8.9/10 15-day trial Free trial✓ 2 of 2 features Visit Overloud

GENOME leads on 3 checks, TH-U on 0, and 3 are even. Who comes out ahead on the 6 yes/no, price and count checks where we have data for both products. The editor score weighs everything else too.

Our verdict

  • Highest scoreGENOME · 9.1/10
  • Free planonly GENOME
  • Free trialboth

GENOME scores higher on our rubric for guitar amp software: 9.1 against 8.9 out of 10; our editors rank them #3 and #5.

GENOME leads on amp models: 24 models versus 16 models. GENOME leads on cabinet models: 16 models versus 15 models. GENOME leads on effects count: 65 effects versus 16 effects.

GENOME is the better fit for cross-platform users wanting AI and standalone use. TH-U is the better fit for captured-rig playback and advanced tone shaping.

  • GENOME fits best

    Cross-platform users wanting AI and standalone use

  • TH-U fits best

    Captured-rig playback and advanced tone shaping

Advertiser disclosure: iTechGuides is reader-supported. Vendors can pay for top positions in our rankings and for a place on other products' pages, and we may earn a commission when you click some links. Bought places stand at the number bought; this page and our disclosure say so. Paying vendors may get a fuller, more detailed review from our editors, and that review can change their score. How we rank.

Side by side

Feature GENOME 9.1/10 Visit ↗ TH-U 8.9/10 Visit ↗
At a glance
Editor score 9.1 8.9
Ranking #3 in Guitar Amp Software #5 in Guitar Amp Software
Best for Cross-platform users wanting AI and standalone use Captured-rig playback and advanced tone shaping
Pricing model Free plan + paid Paid
Starting price — €89 one-time
Free plan ✓ (best) Not checked yet
Free trial 14 days 15 days
Free trial length 14 days 15 days
Deployment Desktop, Mobile Desktop, Mobile
Platforms Windows, macOS, iOS Windows, macOS, iOS
Support Tickets, Docs Docs
Built for Solo, Small business, Mid-market Solo, Small business, Mid-market
Features GENOME 2/2 · TH-U 2/2
Standalone app ✓ ✓
IR loader ✓ ✓
Specs
Amp models 24 models (best) 16 models
Cabinet models 16 models (best) 15 models
Effects count 65 effects (best) 16 effects
Plugin formats VST3, AU, AAX AudioUnit, VST, AAX64
Supported platforms macOS, Windows macOS, Windows
Our review
Pros
  • Standalone and DAW plug-in operation across Windows, macOS, and iOS
  • AI-enabled amplifier components plus CODEX capture playback
  • Flexible routing, MIDI mapping, automation, and integrated IR loading
  • Captured-rig playback with Rig Player and extensive preset libraries
  • Flexible parallel routing, IR tools and Amp Tweak controls
  • Standalone, DAW plug-in and MIDI support across desktop platforms
Cons
  • Desktop and iOS require separate licenses unless using an Access Pass
  • GENOME Intro has fewer amplifiers, pedals, cabinets, and studio effects
  • The product is focused on guitar and bass tone shaping rather than broader production
  • THU Premium requires a €299 one-time purchase
  • THU Metal has a narrower model and effect collection
  • The iOS version is separate from the macOS and Windows application
Our verdict

GENOME is an amp-modeling and tone-shaping platform from Two notes Audio Engineering for guitarists, bassists, producers, and engineers. It runs as a standalone application or as a VST3, AU, or AAX plug-in inside compatible DAWs. The…

Read the review →

TH-U combines amplifier and cabinet modeling, captured-rig playback, effects, impulse-response processing, MIDI control and live performance tools. It is designed for guitarists, bassists, producers and performers who want both ready-made…

Read the review →
  1. GENOMEGuitar Amp Software 9.1Free plan · 14-day trial
  2. TH-UGuitar Amp Software 8.915-day trial

Strengths and trade-offs

  • GENOME — where it wins

    • Standalone and DAW plug-in operation across Windows, macOS, and iOS
    • AI-enabled amplifier components plus CODEX capture playback
    • Flexible routing, MIDI mapping, automation, and integrated IR loading

    Where it doesn't

    • Desktop and iOS require separate licenses unless using an Access Pass
    • GENOME Intro has fewer amplifiers, pedals, cabinets, and studio effects
    • The product is focused on guitar and bass tone shaping rather than broader production

  • TH-U — where it wins

    • Captured-rig playback with Rig Player and extensive preset libraries
    • Flexible parallel routing, IR tools and Amp Tweak controls
    • Standalone, DAW plug-in and MIDI support across desktop platforms

    Where it doesn't

    • THU Premium requires a €299 one-time purchase
    • THU Metal has a narrower model and effect collection
    • The iOS version is separate from the macOS and Windows application

More comparisons

All guitar amp software comparisons → · Full ranking →

Reviewed by iTechGuides Editors · Editorial team · Updated Oct 2026

Last updated · How we research and update